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Intracellular Cholesterol Pools Regulate Oncogenic Signaling and Epigenetic Circuitries in Early T-cell Precursor Acute Lymphoblastic Leukemia.
Rashkovan M, Albero R, Gianni F, Perez-Duran P, Miller HI, Mackey AL, Paietta EM, Tallman MS, Rowe JM, Litzow MR, Wiernik PH, Luger S, Sulis ML, Soni RK, Ferrando AA. Rashkovan M, et al. Among authors: soni rk. Cancer Discov. 2022 Mar 1;12(3):856-871. doi: 10.1158/2159-8290.CD-21-0551. Cancer Discov. 2022. PMID: 34711640 Free PMC article.
Altered Nuclear Export Signal Recognition as a Driver of Oncogenesis.
Taylor J, Sendino M, Gorelick AN, Pastore A, Chang MT, Penson AV, Gavrila EI, Stewart C, Melnik EM, Herrejon Chavez F, Bitner L, Yoshimi A, Lee SC, Inoue D, Liu B, Zhang XJ, Mato AR, Dogan A, Kharas MG, Chen Y, Wang D, Soni RK, Hendrickson RC, Prieto G, Rodriguez JA, Taylor BS, Abdel-Wahab O. Taylor J, et al. Among authors: soni rk. Cancer Discov. 2019 Oct;9(10):1452-1467. doi: 10.1158/2159-8290.CD-19-0298. Epub 2019 Jul 8. Cancer Discov. 2019. PMID: 31285298 Free PMC article.
Super-enhancer hypermutation alters oncogene expression in B cell lymphoma.
Bal E, Kumar R, Hadigol M, Holmes AB, Hilton LK, Loh JW, Dreval K, Wong JCH, Vlasevska S, Corinaldesi C, Soni RK, Basso K, Morin RD, Khiabanian H, Pasqualucci L, Dalla-Favera R. Bal E, et al. Among authors: soni rk. Nature. 2022 Jul;607(7920):808-815. doi: 10.1038/s41586-022-04906-8. Epub 2022 Jul 6. Nature. 2022. PMID: 35794478 Free PMC article.
LZTR1 Mutation Mediates Oncogenesis through Stabilization of EGFR and AXL.
Ko A, Hasanain M, Oh YT, D'Angelo F, Sommer D, Frangaj B, Tran S, Bielle F, Pollo B, Paterra R, Mokhtari K, Soni RK, Peyre M, Eoli M, Papi L, Kalamarides M, Sanson M, Iavarone A, Lasorella A. Ko A, et al. Among authors: soni rk. Cancer Discov. 2023 Mar 1;13(3):702-723. doi: 10.1158/2159-8290.CD-22-0376. Cancer Discov. 2023. PMID: 36445254
A Druggable FOXA1-Glucocorticoid Receptor Transcriptional Axis Drives Tumor Growth in a Subset of Non-Small Cell Lung Cancer.
Dorso M, Patel PT, Pankov A, Boyer JA, Soni RK, Del Priore IS, Hayatt O, Kulick A, Hagen CJ, de Stanchina E, Junttila MR, Daemen A, Friedman LS, Hendrickson RC, Chandarlapaty S. Dorso M, et al. Among authors: soni rk. Cancer Res Commun. 2023 Sep 7;3(9):1788-1799. doi: 10.1158/2767-9764.CRC-23-0310. eCollection 2023 Sep. Cancer Res Commun. 2023. PMID: 37691854 Free PMC article.
STK25 inhibits PKA signaling by phosphorylating PRKAR1A.
Zhang X, Wang BZ, Kim M, Nash TR, Liu B, Rao J, Lock R, Tamargo M, Soni RK, Belov J, Li E, Vunjak-Novakovic G, Fine B. Zhang X, et al. Among authors: soni rk. Cell Rep. 2022 Aug 16;40(7):111203. doi: 10.1016/j.celrep.2022.111203. Cell Rep. 2022. PMID: 35977512 Free PMC article.
KMT2D acetylation by CREBBP reveals a cooperative functional interaction at enhancers in normal and malignant germinal center B cells.
Vlasevska S, Garcia-Ibanez L, Duval R, Holmes AB, Jahan R, Cai B, Kim A, Mo T, Basso K, Soni RK, Bhagat G, Dalla-Favera R, Pasqualucci L. Vlasevska S, et al. Among authors: soni rk. Proc Natl Acad Sci U S A. 2023 Mar 14;120(11):e2218330120. doi: 10.1073/pnas.2218330120. Epub 2023 Mar 9. Proc Natl Acad Sci U S A. 2023. PMID: 36893259 Free PMC article.
206 results