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A distinct core regulatory module enforces oncogene expression in KMT2A-rearranged leukemia.
Harada T, Heshmati Y, Kalfon J, Perez MW, Xavier Ferrucio J, Ewers J, Hubbell Engler B, Kossenkov A, Ellegast JM, Yi JS, Bowker A, Zhu Q, Eagle K, Liu T, Kai Y, Dempster JM, Kugener G, Wickramasinghe J, Herbert ZT, Li CH, Vrabič Koren J, Weinstock DM, Paralkar VR, Nabet B, Lin CY, Dharia NV, Stegmaier K, Orkin SH, Pimkin M. Harada T, et al. Among authors: liu t. Genes Dev. 2022 Mar 1;36(5-6):368-389. doi: 10.1101/gad.349284.121. Epub 2022 Mar 17. Genes Dev. 2022. PMID: 35301220 Free PMC article.
The epigenetic state of the cell of origin defines mechanisms of leukemogenesis.
Li Z, Fierstein S, Tanaka-Yano M, Frenis K, Chen CC, Wang D, Falchetti M, Côté P, Curran C, Lu K, Liu T, Orkin S, Li H, Lummertz da Rocha E, Hu S, Zhu Q, Rowe RG. Li Z, et al. Among authors: liu t. Leukemia. 2024 Oct 1. doi: 10.1038/s41375-024-02428-y. Online ahead of print. Leukemia. 2024. PMID: 39354203
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