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The E3 ligase COP1 promotes ERα signaling and suppresses EMT in breast cancer.
Tang SC, Lion Q, Peulen O, Chariot P, Lavergne A, Mayer A, Fuster PA, Close P, Klein S, Florin A, Büttner R, Nemazanyy I, Shostak K, Chariot A. Tang SC, et al. Among authors: nemazanyy i. Oncogene. 2022 Jan;41(2):173-190. doi: 10.1038/s41388-021-02038-3. Epub 2021 Oct 29. Oncogene. 2022. PMID: 34716429
Elp3-mediated codon-dependent translation promotes mTORC2 activation and regulates macrophage polarization.
Chen D, Nemazanyy I, Peulen O, Shostak K, Xu X, Tang SC, Wathieu C, Turchetto S, Tielens S, Nguyen L, Close P, Desmet C, Klein S, Florin A, Büttner R, Petrellis G, Dewals B, Chariot A. Chen D, et al. Among authors: nemazanyy i. EMBO J. 2022 Sep 15;41(18):e109353. doi: 10.15252/embj.2021109353. Epub 2022 Aug 3. EMBO J. 2022. PMID: 35920020 Free PMC article.
Loss of Elp3 blocks intestinal tuft cell differentiation via an mTORC1-Atf4 axis.
Wathieu C, Lavergne A, Xu X, Rolot M, Nemazanyy I, Shostak K, El Hachem N, Maurizy C, Leemans C, Close P, Nguyen L, Desmet C, Tielens S, Dewals BG, Chariot A. Wathieu C, et al. Among authors: nemazanyy i. EMBO J. 2024 Sep;43(18):3916-3947. doi: 10.1038/s44318-024-00184-4. Epub 2024 Jul 31. EMBO J. 2024. PMID: 39085648 Free PMC article.
mTOR inhibition suppresses salinomycin-induced ferroptosis in breast cancer stem cells by ironing out mitochondrial dysfunctions.
Cosialls E, Pacreau E, Duruel C, Ceccacci S, Elhage R, Desterke C, Roger K, Guerrera C, Ducloux R, Souquere S, Pierron G, Nemazanyy I, Kelly M, Dalmas E, Chang Y, Goffin V, Mehrpour M, Hamaï A. Cosialls E, et al. Among authors: nemazanyy i. Cell Death Dis. 2023 Nov 15;14(11):744. doi: 10.1038/s41419-023-06262-5. Cell Death Dis. 2023. PMID: 37968262 Free PMC article.
75 results