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The hepatocyte export carrier inhibition assay improves the separation of hepatotoxic from non-hepatotoxic compounds.
Brecklinghaus T, Albrecht W, Kappenberg F, Duda J, Vartak N, Edlund K, Marchan R, Ghallab A, Cadenas C, Günther G, Leist M, Zhang M, Gardner I, Reinders J, Russel FG, Foster AJ, Williams DP, Damle-Vartak A, Grandits M, Ecker G, Kittana N, Rahnenführer J, Hengstler JG. Brecklinghaus T, et al. Among authors: vartak n. Chem Biol Interact. 2022 Jan 5;351:109728. doi: 10.1016/j.cbi.2021.109728. Epub 2021 Oct 27. Chem Biol Interact. 2022. PMID: 34717914 Free article.
In vitro/in silico prediction of drug induced steatosis in relation to oral doses and blood concentrations by the Nile Red assay.
Brecklinghaus T, Albrecht W, Duda J, Kappenberg F, Gründler L, Edlund K, Marchan R, Ghallab A, Cadenas C, Rieck A, Vartak N, Tolosa L, Castell JV, Gardner I, Halilbasic E, Trauner M, Ullrich A, Zeigerer A, Demirci Turgunbayer Ö, Damm G, Seehofer D, Rahnenführer J, Hengstler JG. Brecklinghaus T, et al. Among authors: vartak n. Toxicol Lett. 2022 Sep 1;368:33-46. doi: 10.1016/j.toxlet.2022.08.006. Epub 2022 Aug 10. Toxicol Lett. 2022. PMID: 35963427
Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations.
Albrecht W, Kappenberg F, Brecklinghaus T, Stoeber R, Marchan R, Zhang M, Ebbert K, Kirschner H, Grinberg M, Leist M, Moritz W, Cadenas C, Ghallab A, Reinders J, Vartak N, van Thriel C, Golka K, Tolosa L, Castell JV, Damm G, Seehofer D, Lampen A, Braeuning A, Buhrke T, Behr AC, Oberemm A, Gu X, Kittana N, van de Water B, Kreiling R, Fayyaz S, van Aerts L, Smedsrød B, Ellinger-Ziegelbauer H, Steger-Hartmann T, Gundert-Remy U, Zeigerer A, Ullrich A, Runge D, Lee SML, Schiergens TS, Kuepfer L, Aguayo-Orozco A, Sachinidis A, Edlund K, Gardner I, Rahnenführer J, Hengstler JG. Albrecht W, et al. Among authors: vartak n. Arch Toxicol. 2019 Jun;93(6):1609-1637. doi: 10.1007/s00204-019-02492-9. Epub 2019 Jun 27. Arch Toxicol. 2019. PMID: 31250071
REPLY.
Vartak N, Hengstler JG. Vartak N, et al. Hepatology. 2021 Aug;74(2):1133. doi: 10.1002/hep.31744. Epub 2021 Jul 26. Hepatology. 2021. PMID: 33559147 No abstract available.
Reply.
Vartak N, Hengstler JG. Vartak N, et al. Hepatology. 2022 Feb;75(2):493-494. doi: 10.1002/hep.32168. Epub 2021 Dec 7. Hepatology. 2022. PMID: 34546585 No abstract available.
Identification of an FXR-modulated liver-intestine hybrid state in iPSC-derived hepatocyte-like cells.
Nell P, Kattler K, Feuerborn D, Hellwig B, Rieck A, Salhab A, Lepikhov K, Gasparoni G, Thomitzek A, Belgasmi K, Blüthgen N, Morkel M, Küppers-Munther B, Godoy P, Hay DC, Cadenas C, Marchan R, Vartak N, Edlund K, Rahnenführer J, Walter J, Hengstler JG. Nell P, et al. Among authors: vartak n. J Hepatol. 2022 Nov;77(5):1386-1398. doi: 10.1016/j.jhep.2022.07.009. Epub 2022 Jul 19. J Hepatol. 2022. PMID: 35863491 Free article.
Reply.
Vartak N, Hengstler JG. Vartak N, et al. Hepatology. 2022 Apr;75(4):1061-1062. doi: 10.1002/hep.32297. Epub 2022 Jan 11. Hepatology. 2022. PMID: 34953145 No abstract available.
The ascending pathophysiology of cholestatic liver disease.
Jansen PL, Ghallab A, Vartak N, Reif R, Schaap FG, Hampe J, Hengstler JG. Jansen PL, et al. Among authors: vartak n. Hepatology. 2017 Feb;65(2):722-738. doi: 10.1002/hep.28965. Hepatology. 2017. PMID: 27981592 Review.
43 results