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Microbiota-derived acetate enables the metabolic fitness of the brain innate immune system during health and disease.
Erny D, Dokalis N, Mezö C, Castoldi A, Mossad O, Staszewski O, Frosch M, Villa M, Fuchs V, Mayer A, Neuber J, Sosat J, Tholen S, Schilling O, Vlachos A, Blank T, Gomez de Agüero M, Macpherson AJ, Pearce EJ, Prinz M. Erny D, et al. Among authors: macpherson aj. Cell Metab. 2021 Nov 2;33(11):2260-2276.e7. doi: 10.1016/j.cmet.2021.10.010. Cell Metab. 2021. PMID: 34731656 Free article.
Metabolites from intestinal microbes shape Treg.
Geuking MB, McCoy KD, Macpherson AJ. Geuking MB, et al. Among authors: macpherson aj. Cell Res. 2013 Dec;23(12):1339-40. doi: 10.1038/cr.2013.125. Epub 2013 Sep 10. Cell Res. 2013. PMID: 24018374 Free PMC article.
The maternal microbiota drives early postnatal innate immune development.
Gomez de Agüero M, Ganal-Vonarburg SC, Fuhrer T, Rupp S, Uchimura Y, Li H, Steinert A, Heikenwalder M, Hapfelmeier S, Sauer U, McCoy KD, Macpherson AJ. Gomez de Agüero M, et al. Among authors: macpherson aj. Science. 2016 Mar 18;351(6279):1296-302. doi: 10.1126/science.aad2571. Science. 2016. PMID: 26989247
The immunological functions of the Appendix: An example of redundancy?
Girard-Madoux MJH, Gomez de Agüero M, Ganal-Vonarburg SC, Mooser C, Belz GT, Macpherson AJ, Vivier E. Girard-Madoux MJH, et al. Among authors: macpherson aj. Semin Immunol. 2018 Apr;36:31-44. doi: 10.1016/j.smim.2018.02.005. Epub 2018 Mar 2. Semin Immunol. 2018. PMID: 29503124 Review.
Antibodies Set Boundaries Limiting Microbial Metabolite Penetration and the Resultant Mammalian Host Response.
Uchimura Y, Fuhrer T, Li H, Lawson MA, Zimmermann M, Yilmaz B, Zindel J, Ronchi F, Sorribas M, Hapfelmeier S, Ganal-Vonarburg SC, Gomez de Agüero M, McCoy KD, Sauer U, Macpherson AJ. Uchimura Y, et al. Among authors: macpherson aj. Immunity. 2018 Sep 18;49(3):545-559.e5. doi: 10.1016/j.immuni.2018.08.004. Epub 2018 Sep 4. Immunity. 2018. PMID: 30193848 Free PMC article.
Different effects of constitutive and induced microbiota modulation on microglia in a mouse model of Alzheimer's disease.
Mezö C, Dokalis N, Mossad O, Staszewski O, Neuber J, Yilmaz B, Schnepf D, de Agüero MG, Ganal-Vonarburg SC, Macpherson AJ, Meyer-Luehmann M, Staeheli P, Blank T, Prinz M, Erny D. Mezö C, et al. Among authors: macpherson aj. Acta Neuropathol Commun. 2020 Jul 29;8(1):119. doi: 10.1186/s40478-020-00988-5. Acta Neuropathol Commun. 2020. PMID: 32727612 Free PMC article.
Long-term evolution and short-term adaptation of microbiota strains and sub-strains in mice.
Yilmaz B, Mooser C, Keller I, Li H, Zimmermann J, Bosshard L, Fuhrer T, Gomez de Agüero M, Trigo NF, Tschanz-Lischer H, Limenitakis JP, Hardt WD, McCoy KD, Stecher B, Excoffier L, Sauer U, Ganal-Vonarburg SC, Macpherson AJ. Yilmaz B, et al. Among authors: macpherson aj. Cell Host Microbe. 2021 Apr 14;29(4):650-663.e9. doi: 10.1016/j.chom.2021.02.001. Epub 2021 Mar 3. Cell Host Microbe. 2021. PMID: 33662276 Free article.
Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition.
Colombo AV, Sadler RK, Llovera G, Singh V, Roth S, Heindl S, Sebastian Monasor L, Verhoeven A, Peters F, Parhizkar S, Kamp F, Gomez de Aguero M, MacPherson AJ, Winkler E, Herms J, Benakis C, Dichgans M, Steiner H, Giera M, Haass C, Tahirovic S, Liesz A. Colombo AV, et al. Among authors: macpherson aj. Elife. 2021 Apr 13;10:e59826. doi: 10.7554/eLife.59826. Elife. 2021. PMID: 33845942 Free PMC article.
248 results