Iasonos A - Search Results

1

Controlled backfill in oncology dose-finding trials.

Dehbi HM, O'Quigley J, Iasonos A. Dehbi HM, et al. Among authors: iasonos a. Contemp Clin Trials. 2021 Dec;111:106605. doi: 10.1016/j.cct.2021.106605. Epub 2021 Oct 30. Contemp Clin Trials. 2021. PMID: 34743987

2

A comprehensive comparison of the continual reassessment method to the standard 3 + 3 dose escalation scheme in Phase I dose-finding studies.

Iasonos A, Wilton AS, Riedel ER, Seshan VE, Spriggs DR. Iasonos A, et al. Clin Trials. 2008;5(5):465-77. doi: 10.1177/1740774508096474. Clin Trials. 2008. PMID: 18827039 Free PMC article.

3

Continual reassessment and related designs in dose-finding studies.

Iasonos A, O'Quigley J. Iasonos A, et al. Stat Med. 2011 Jul 30;30(17):2057-61. doi: 10.1002/sim.4215. Epub 2011 Feb 24. Stat Med. 2011. PMID: 21351292 Free PMC article. No abstract available.

4

Incorporating lower grade toxicity information into dose finding designs.

Iasonos A, Zohar S, O'Quigley J. Iasonos A, et al. Clin Trials. 2011 Aug;8(4):370-9. doi: 10.1177/1740774511410732. Clin Trials. 2011. PMID: 21835856 Free PMC article.

5

The impact of non-drug-related toxicities on the estimation of the maximum tolerated dose in phase I trials.

Iasonos A, Gounder M, Spriggs DR, Gerecitano JF, Hyman DM, Zohar S, O'Quigley J. Iasonos A, et al. Clin Cancer Res. 2012 Oct 1;18(19):5179-87. doi: 10.1158/1078-0432.CCR-12-0726. Epub 2012 Jul 23. Clin Cancer Res. 2012. PMID: 22825582 Free PMC article.

6

Interplay of priors and skeletons in two-stage continual reassessment method.

Iasonos A, O'Quigley J. Iasonos A, et al. Stat Med. 2012 Dec 30;31(30):4321-36. doi: 10.1002/sim.5559. Epub 2012 Aug 15. Stat Med. 2012. PMID: 22893483 Free PMC article.

7

Design considerations for dose-expansion cohorts in phase I trials.

Iasonos A, O'Quigley J. Iasonos A, et al. J Clin Oncol. 2013 Nov 1;31(31):4014-21. doi: 10.1200/JCO.2012.47.9949. Epub 2013 Oct 7. J Clin Oncol. 2013. PMID: 24101039 Free PMC article.

8

Adaptive dose-finding studies: a review of model-guided phase I clinical trials.

Iasonos A, O'Quigley J. Iasonos A, et al. J Clin Oncol. 2014 Aug 10;32(23):2505-11. doi: 10.1200/JCO.2013.54.6051. Epub 2014 Jun 30. J Clin Oncol. 2014. PMID: 24982451 Free PMC article. Review.

9

Bridging Solutions in Dose Finding Problems.

O'Quigley J, Iasonos A. O'Quigley J, et al. Among authors: iasonos a. Stat Biopharm Res. 2014 May 1;6(2):185-197. doi: 10.1080/19466315.2014.906365. Stat Biopharm Res. 2014. PMID: 25071878 Free PMC article.

10

Predictors of early treatment discontinuation in patients enrolled on Phase I oncology trials.

Hyman DM, Eaton AA, Gounder MM, Pamer EG, Pettiford J, Carvajal RD, Ivy SP, Iasonos A, Spriggs DR. Hyman DM, et al. Among authors: iasonos a. Oncotarget. 2015 Aug 7;6(22):19316-27. doi: 10.18632/oncotarget.2909. Oncotarget. 2015. PMID: 25682870 Free PMC article. Clinical Trial.

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