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A Remote Secondary Binding Pocket Promotes Heteromultivalent Targeting of DC-SIGN.
Wawrzinek R, Wamhoff EC, Lefebre J, Rentzsch M, Bachem G, Domeniconi G, Schulze J, Fuchsberger FF, Zhang H, Modenutti C, Schnirch L, Marti MA, Schwardt O, Bräutigam M, Guberman M, Hauck D, Seeberger PH, Seitz O, Titz A, Ernst B, Rademacher C. Wawrzinek R, et al. Among authors: bachem g. J Am Chem Soc. 2021 Nov 17;143(45):18977-18988. doi: 10.1021/jacs.1c07235. Epub 2021 Nov 8. J Am Chem Soc. 2021. PMID: 34748320 Free PMC article.
A Specific, Glycomimetic Langerin Ligand for Human Langerhans Cell Targeting.
Wamhoff EC, Schulze J, Bellmann L, Rentzsch M, Bachem G, Fuchsberger FF, Rademacher J, Hermann M, Del Frari B, van Dalen R, Hartmann D, van Sorge NM, Seitz O, Stoitzner P, Rademacher C. Wamhoff EC, et al. Among authors: bachem g. ACS Cent Sci. 2019 May 22;5(5):808-820. doi: 10.1021/acscentsci.9b00093. Epub 2019 May 10. ACS Cent Sci. 2019. PMID: 31139717 Free PMC article.
Rational Design of a DNA-Scaffolded High-Affinity Binder for Langerin.
Bachem G, Wamhoff EC, Silberreis K, Kim D, Baukmann H, Fuchsberger F, Dernedde J, Rademacher C, Seitz O. Bachem G, et al. Angew Chem Int Ed Engl. 2020 Nov 16;59(47):21016-21022. doi: 10.1002/anie.202006880. Epub 2020 Sep 15. Angew Chem Int Ed Engl. 2020. PMID: 32749019 Free PMC article.