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Transient mTOR inhibition rescues 4-1BB CAR-Tregs from tonic signal-induced dysfunction.
Lamarthée B, Marchal A, Charbonnier S, Blein T, Leon J, Martin E, Rabaux L, Vogt K, Titeux M, Delville M, Vinçon H, Six E, Pallet N, Michonneau D, Anglicheau D, Legendre C, Taupin JL, Nemazanyy I, Sawitzki B, Latour S, Cavazzana M, André I, Zuber J. Lamarthée B, et al. Among authors: cavazzana m. Nat Commun. 2021 Nov 8;12(1):6446. doi: 10.1038/s41467-021-26844-1. Nat Commun. 2021. PMID: 34750385 Free PMC article.
A Nontoxic Transduction Enhancer Enables Highly Efficient Lentiviral Transduction of Primary Murine T Cells and Hematopoietic Stem Cells.
Delville M, Soheili T, Bellier F, Durand A, Denis A, Lagresle-Peyrou C, Cavazzana M, Andre-Schmutz I, Six E. Delville M, et al. Among authors: cavazzana m. Mol Ther Methods Clin Dev. 2018 Aug 8;10:341-347. doi: 10.1016/j.omtm.2018.08.002. eCollection 2018 Sep 21. Mol Ther Methods Clin Dev. 2018. PMID: 30191160 Free PMC article.
Baboon envelope LVs efficiently transduced human adult, fetal, and progenitor T cells and corrected SCID-X1 T-cell deficiency.
Bernadin O, Amirache F, Girard-Gagnepain A, Moirangthem RD, Lévy C, Ma K, Costa C, Nègre D, Reimann C, Fenard D, Cieslak A, Asnafi V, Sadek H, Mhaidly R, Cavazzana M, Lagresle-Peyrou C, Cosset FL, André I, Verhoeyen E. Bernadin O, et al. Among authors: cavazzana m. Blood Adv. 2019 Feb 12;3(3):461-475. doi: 10.1182/bloodadvances.2018027508. Blood Adv. 2019. PMID: 30755435 Free PMC article.
Ex vivo generated human T-lymphoid progenitors as a tool to accelerate immune reconstitution after partially HLA compatible hematopoietic stem cell transplantation or after gene therapy.
André I, Simons L, Ma K, Moirangthem RD, Diana JS, Magrin E, Couzin C, Magnani A, Cavazzana M. André I, et al. Among authors: cavazzana m. Bone Marrow Transplant. 2019 Aug;54(Suppl 2):749-755. doi: 10.1038/s41409-019-0599-9. Bone Marrow Transplant. 2019. PMID: 31431705 Review.
Extensive multilineage analysis in patients with mixed chimerism after allogeneic transplantation for sickle cell disease: insight into hematopoiesis and engraftment thresholds for gene therapy.
Magnani A, Pondarré C, Bouazza N, Magalon J, Miccio A, Six E, Roudaut C, Arnaud C, Kamdem A, Touzot F, Gabrion A, Magrin E, Couzin C, Fusaro M, André I, Vernant JP, Gluckman E, Bernaudin F, Bories D, Cavazzana M. Magnani A, et al. Among authors: cavazzana m. Haematologica. 2020 May;105(5):1240-1247. doi: 10.3324/haematol.2019.227561. Epub 2019 Sep 19. Haematologica. 2020. PMID: 31537695 Free PMC article.
Clonal tracking in gene therapy patients reveals a diversity of human hematopoietic differentiation programs.
Six E, Guilloux A, Denis A, Lecoules A, Magnani A, Vilette R, Male F, Cagnard N, Delville M, Magrin E, Caccavelli L, Roudaut C, Plantier C, Sobrino S, Gregg J, Nobles CL, Everett JK, Hacein-Bey-Abina S, Galy A, Fischer A, Thrasher AJ, André I, Cavazzana M, Bushman FD. Six E, et al. Among authors: cavazzana m. Blood. 2020 Apr 9;135(15):1219-1231. doi: 10.1182/blood.2019002350. Blood. 2020. PMID: 32040546 Free PMC article. Clinical Trial.
Donor-targeted serotherapy as a rescue therapy for steroid-resistant acute GVHD after HLA-mismatched kidney transplantation.
Zuber J, Boyer O, Neven B, Jollet I, Renac V, Berthaud R, Levy R, Lamarthée B, Visentin J, Marchal A, Gouge-Biebuyck N, Godron-Dubrasquet A, Aladjidi N, Rabah MO, Winter S, Léon J, Dussiot M, Rabant M, Krid S, Krug P, Charbit M, Lacaille F, André I, Cavazzana M, Llanas B, Allard L, Pirenne F, Gross S, Djoudi R, Tiberghien P, Taupin JL, Blanche S, Salomon R. Zuber J, et al. Among authors: cavazzana m. Am J Transplant. 2020 Aug;20(8):2243-2253. doi: 10.1111/ajt.15827. Epub 2020 Mar 10. Am J Transplant. 2020. PMID: 32065452 Free article.
173 results