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Effect of anti-interleukin drugs in patients with COVID-19 and signs of cytokine release syndrome (COV-AID): a factorial, randomised, controlled trial.
Declercq J, Van Damme KFA, De Leeuw E, Maes B, Bosteels C, Tavernier SJ, De Buyser S, Colman R, Hites M, Verschelden G, Fivez T, Moerman F, Demedts IK, Dauby N, De Schryver N, Govaerts E, Vandecasteele SJ, Van Laethem J, Anguille S, van der Hilst J, Misset B, Slabbynck H, Wittebole X, Liénart F, Legrand C, Buyse M, Stevens D, Bauters F, Seys LJM, Aegerter H, Smole U, Bosteels V, Hoste L, Naesens L, Haerynck F, Vandekerckhove L, Depuydt P, van Braeckel E, Rottey S, Peene I, Van Der Straeten C, Hulstaert F, Lambrecht BN. Declercq J, et al. Among authors: smole u. Lancet Respir Med. 2021 Dec;9(12):1427-1438. doi: 10.1016/S2213-2600(21)00377-5. Epub 2021 Oct 29. Lancet Respir Med. 2021. PMID: 34756178 Free PMC article. Clinical Trial.
TIM3+ TRBV11-2 T cells and IFNγ signature in patrolling monocytes and CD16+ NK cells delineate MIS-C.
Hoste L, Roels L, Naesens L, Bosteels V, Vanhee S, Dupont S, Bosteels C, Browaeys R, Vandamme N, Verstaen K, Roels J, Van Damme KFA, Maes B, De Leeuw E, Declercq J, Aegerter H, Seys L, Smole U, De Prijck S, Vanheerswynghels M, Claes K, Debacker V, Van Isterdael G, Backers L, Claes KBM, Bastard P, Jouanguy E, Zhang SY, Mets G, Dehoorne J, Vandekerckhove K, Schelstraete P, Willems J; MIS-C Clinicians; Stordeur P, Janssens S, Beyaert R, Saeys Y, Casanova JL, Lambrecht BN, Haerynck F, Tavernier SJ. Hoste L, et al. Among authors: smole u. J Exp Med. 2022 Feb 7;219(2):e20211381. doi: 10.1084/jem.20211381. Epub 2021 Dec 16. J Exp Med. 2022. PMID: 34914824 Free PMC article.
The STE20 kinase TAOK3 controls the development of house dust mite-induced asthma in mice.
Maes B, Smole U, Vanderkerken M, Deswarte K, Van Moorleghem J, Vergote K, Vanheerswynghels M, De Wolf C, De Prijck S, Debeuf N, Pavie B, Toussaint W, Janssens S, Savvides S, Lambrecht BN, Hammad H. Maes B, et al. Among authors: smole u. J Allergy Clin Immunol. 2022 Apr;149(4):1413-1427.e2. doi: 10.1016/j.jaci.2021.08.020. Epub 2021 Sep 8. J Allergy Clin Immunol. 2022. PMID: 34506849
Art v 1 IgE epitopes of patients and humanized mice are conformational.
Zabel M, Weber M, Kratzer B, Köhler C, Jahn-Schmid B, Gadermaier G, Gattinger P, Bidovec-Stojkovič U, Korošec P, Smole U, Wurzinger G, Chen KW, Panaitescu CB, Klimek L, Pablos I, Niespodziana K, Neunkirchner A, Keller W, Valenta R, Pickl WF. Zabel M, et al. Among authors: smole u. J Allergy Clin Immunol. 2022 Oct;150(4):920-930. doi: 10.1016/j.jaci.2022.04.031. Epub 2022 Jun 21. J Allergy Clin Immunol. 2022. PMID: 35738928 Free article.
Serum amyloid A is a soluble pattern recognition receptor that drives type 2 immunity.
Smole U, Gour N, Phelan J, Hofer G, Köhler C, Kratzer B, Tauber PA, Xiao X, Yao N, Dvorak J, Caraballo L, Puerta L, Rosskopf S, Chakir J, Malle E, Lane AP, Pickl WF, Lajoie S, Wills-Karp M. Smole U, et al. Nat Immunol. 2020 Jul;21(7):756-765. doi: 10.1038/s41590-020-0698-1. Epub 2020 Jun 22. Nat Immunol. 2020. PMID: 32572240 Free PMC article.
Prevention of allergy by virus-like nanoparticles (VNP) delivering shielded versions of major allergens in a humanized murine allergy model.
Kratzer B, Köhler C, Hofer S, Smole U, Trapin D, Iturri J, Pum D, Kienzl P, Elbe-Bürger A, Gattinger P, Mittermann I, Linhart B, Gadermaier G, Jahn-Schmid B, Neunkirchner A, Valenta R, Pickl WF. Kratzer B, et al. Among authors: smole u. Allergy. 2019 Feb;74(2):246-260. doi: 10.1111/all.13573. Epub 2018 Nov 5. Allergy. 2019. PMID: 30035810 Free PMC article.
26 results