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319 results

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Autocrine vitamin D signaling switches off pro-inflammatory programs of TH1 cells.
Chauss D, Freiwald T, McGregor R, Yan B, Wang L, Nova-Lamperti E, Kumar D, Zhang Z, Teague H, West EE, Vannella KM, Ramos-Benitez MJ, Bibby J, Kelly A, Malik A, Freeman AF, Schwartz DM, Portilla D, Chertow DS, John S, Lavender P, Kemper C, Lombardi G, Mehta NN, Cooper N, Lionakis MS, Laurence A, Kazemian M, Afzali B. Chauss D, et al. Among authors: mehta nn. Nat Immunol. 2022 Jan;23(1):62-74. doi: 10.1038/s41590-021-01080-3. Epub 2021 Nov 11. Nat Immunol. 2022. PMID: 34764490 Free PMC article.
IFN-γ and TNF-α synergism may provide a link between psoriasis and inflammatory atherogenesis.
Mehta NN, Teague HL, Swindell WR, Baumer Y, Ward NL, Xing X, Baugous B, Johnston A, Joshi AA, Silverman J, Barnes DH, Wolterink L, Nair RP, Stuart PE, Playford M, Voorhees JJ, Sarkar MK, Elder JT, Gallagher K, Ganesh SK, Gudjonsson JE. Mehta NN, et al. Sci Rep. 2017 Oct 23;7(1):13831. doi: 10.1038/s41598-017-14365-1. Sci Rep. 2017. PMID: 29062018 Free PMC article.
Serum active 1,25(OH)2D, but not inactive 25(OH)D vitamin D levels are associated with cardiometabolic and cardiovascular disease risk in psoriasis.
Playford MP, Dey AK, Zierold C, Joshi AA, Blocki F, Bonelli F, Rodante JA, Harrington CL, Rivers JP, Elnabawi YA, Chen MY, Ahlman MA, Teague HL, Mehta NN. Playford MP, et al. Among authors: mehta nn. Atherosclerosis. 2019 Oct;289:44-50. doi: 10.1016/j.atherosclerosis.2019.08.006. Epub 2019 Aug 17. Atherosclerosis. 2019. PMID: 31450013 Free PMC article.
Cells of Myeloid Origin Partly Mediate the Association between Psoriasis Severity and Coronary Plaque.
Teague HL, Aksentijevich M, Stansky E, Silverman JI, Varghese NJ, Dey AK, Elnabawi Y, Goyal A, Dagur PK, Chen MY, McCoy JP, Playford MP, Hourigan C, Gelfand JM, Mehta NN. Teague HL, et al. Among authors: mehta nn. J Invest Dermatol. 2020 Apr;140(4):912-915.e1. doi: 10.1016/j.jid.2019.07.724. Epub 2019 Sep 17. J Invest Dermatol. 2020. PMID: 31539534 Free PMC article. No abstract available.
Hyperlipidaemia and IFNgamma/TNFalpha Synergism are associated with cholesterol crystal formation in Endothelial cells partly through modulation of Lysosomal pH and Cholesterol homeostasis.
Baumer Y, Dey AK, Gutierrez-Huerta CA, Khalil NO, Sekine Y, Sanda GE, Zhuang J, Saxena A, Stempinski E, Elnabawi YA, Dagur PK, Ng Q, Teague HL, Keel A, Rodante JA, Boisvert WA, Tsoi LC, Gudjonsson JE, Bleck CKE, Chen MY, Bluemke DA, Gelfand JM, Schwartz DM, Kruth HS, Powell-Wiley TM, Playford MP, Mehta NN. Baumer Y, et al. Among authors: mehta nn. EBioMedicine. 2020 Sep;59:102876. doi: 10.1016/j.ebiom.2020.102876. Epub 2020 Jul 6. EBioMedicine. 2020. PMID: 32646751 Free PMC article.
An autocrine Vitamin D-driven Th1 shutdown program can be exploited for COVID-19.
McGregor R, Chauss D, Freiwald T, Yan B, Wang L, Nova-Lamperti E, Zhang Z, Teague H, West EE, Bibby J, Kelly A, Malik A, Freeman AF, Schwartz D, Portilla D, John S, Lavender P, Lionakis MS, Mehta NN, Kemper C, Cooper N, Lombardi G, Laurence A, Kazemian M, Afzali B. McGregor R, et al. Among authors: mehta nn. bioRxiv [Preprint]. 2020 Jul 19:2020.07.18.210161. doi: 10.1101/2020.07.18.210161. bioRxiv. 2020. PMID: 32743590 Free PMC article. Preprint.
319 results