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Cell size is a determinant of stem cell potential during aging.
Lengefeld J, Cheng CW, Maretich P, Blair M, Hagen H, McReynolds MR, Sullivan E, Majors K, Roberts C, Kang JH, Steiner JD, Miettinen TP, Manalis SR, Antebi A, Morrison SJ, Lees JA, Boyer LA, Yilmaz ÖH, Amon A. Lengefeld J, et al. Among authors: lees ja. Sci Adv. 2021 Nov 12;7(46):eabk0271. doi: 10.1126/sciadv.abk0271. Epub 2021 Nov 12. Sci Adv. 2021. PMID: 34767451 Free PMC article.
MITF deficiency accelerates GNAQ-driven uveal melanoma.
Phelps GB, Hagen HR, Amsterdam A, Lees JA. Phelps GB, et al. Among authors: lees ja. Proc Natl Acad Sci U S A. 2022 May 10;119(19):e2107006119. doi: 10.1073/pnas.2107006119. Epub 2022 May 5. Proc Natl Acad Sci U S A. 2022. PMID: 35512098 Free PMC article.
In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis.
Roper J, Tammela T, Cetinbas NM, Akkad A, Roghanian A, Rickelt S, Almeqdadi M, Wu K, Oberli MA, Sánchez-Rivera FJ, Park YK, Liang X, Eng G, Taylor MS, Azimi R, Kedrin D, Neupane R, Beyaz S, Sicinska ET, Suarez Y, Yoo J, Chen L, Zukerberg L, Katajisto P, Deshpande V, Bass AJ, Tsichlis PN, Lees J, Langer R, Hynes RO, Chen J, Bhutkar A, Jacks T, Yilmaz ÖH. Roper J, et al. Nat Biotechnol. 2017 Jun;35(6):569-576. doi: 10.1038/nbt.3836. Epub 2017 May 1. Nat Biotechnol. 2017. PMID: 28459449 Free PMC article.
BMI1 is required for melanocyte stem cell maintenance and hair pigmentation.
Wilson MM, Danielian PS, Salus G, Ferretti R, Whittaker CA, Lees JA. Wilson MM, et al. Among authors: lees ja. Pigment Cell Melanoma Res. 2023 Sep;36(5):399-406. doi: 10.1111/pcmr.13088. Epub 2023 May 3. Pigment Cell Melanoma Res. 2023. PMID: 37132544 Free PMC article.
193 results