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Integrative Analysis of the Inflammatory Bowel Disease Serum Metabolome Improves Our Understanding of Genetic Etiology and Points to Novel Putative Therapeutic Targets.
Di'Narzo AF, Houten SM, Kosoy R, Huang R, Vaz FM, Hou R, Wei G, Wang W, Comella PH, Dodatko T, Rogatsky E, Stojmirovic A, Brodmerkel C, Perrigoue J, Hart A, Curran M, Friedman JR, Zhu J, Agrawal M, Cho J, Ungaro R, Dubinsky MC, Sands BE, Suárez-Fariñas M, Schadt EE, Colombel JF, Kasarskis A, Hao K, Argmann C. Di'Narzo AF, et al. Among authors: hart a. Gastroenterology. 2022 Mar;162(3):828-843.e11. doi: 10.1053/j.gastro.2021.11.015. Epub 2021 Nov 13. Gastroenterology. 2022. PMID: 34780722 Free PMC article.
Biopsy and blood-based molecular biomarker of inflammation in IBD.
Argmann C, Hou R, Ungaro RC, Irizar H, Al-Taie Z, Huang R, Kosoy R, Venkat S, Song WM, Di'Narzo AF, Losic B, Hao K, Peters L, Comella PH, Wei G, Atreja A, Mahajan M, Iuga A, Desai PT, Branigan P, Stojmirovic A, Perrigoue J, Brodmerkel C, Curran M, Friedman JR, Hart A, Lamousé-Smith E, Wehkamp J, Mehandru S, Schadt EE, Sands BE, Dubinsky MC, Colombel JF, Kasarskis A, Suárez-Fariñas M. Argmann C, et al. Among authors: hart a. Gut. 2023 Jul;72(7):1271-1287. doi: 10.1136/gutjnl-2021-326451. Epub 2022 Sep 15. Gut. 2023. PMID: 36109152 Free PMC article.
Gene coexpression networks reveal a broad role for lncRNAs in inflammatory bowel disease.
Johnson JL, Sargsyan D, Neiman EM, Hart A, Stojmirovic A, Kosoy R, Irizar H, Suárez-Fariñas M, Song WM, Argmann C, Avey S, Shmuel-Galia L, Vierbuchen T, Bongers G, Sun Y, Edelstein L, Perrigoue J, Towne JE, Hall AO, Fitzgerald KA, Hoebe K. Johnson JL, et al. Among authors: hart a. JCI Insight. 2024 Feb 8;9(3):e168988. doi: 10.1172/jci.insight.168988. JCI Insight. 2024. PMID: 38329124 Free PMC article.
Age-related patterns of microbial dysbiosis in multiplex inflammatory bowel disease families.
Jacobs JP, Spencer EA, Helmus DS, Yang JC, Lagishetty V, Bongers G, Britton G, Gettler K, Reyes-Mercedes P, Hu J, Hart A, Lamousé-Smith E, Wehkamp J, Landers C, Debbas P, Torres J, Colombel JF, Cho J, Peter I, Faith J, Braun J, Dubinsky M. Jacobs JP, et al. Among authors: hart a. Gut. 2024 Nov 11;73(12):1953-1964. doi: 10.1136/gutjnl-2024-332475. Gut. 2024. PMID: 39122361
Gut microbiota strain richness is species specific and affects engraftment.
Chen-Liaw A, Aggarwala V, Mogno I, Haifer C, Li Z, Eggers J, Helmus D, Hart A, Wehkamp J, Lamousé-Smith ESN, Kerby RL, Rey FE, Colombel JF, Kamm MA, Olle B, Norman JM, Menon R, Watson AR, Crossett E, Terveer EM, Keller JJ, Borody TJ, Grinspan A, Paramsothy S, Kaakoush NO, Dubinsky MC, Faith JJ. Chen-Liaw A, et al. Among authors: hart a. Nature. 2025 Jan;637(8045):422-429. doi: 10.1038/s41586-024-08242-x. Epub 2024 Nov 27. Nature. 2025. PMID: 39604726
Diagnosing Crohn's Disease in Presumed Cryptoglandular Perianal Fistulas: An Expert Delphi Consensus on Early Identification of Patients at Risk of Crohn's Disease in Perianal Fistulas (PREFAB).
Munster LJ, Hanna LN, Hart AL, Tozer PJ, Buskens CJ, van der Bilt JDW; TOpCLASS perianal Crohn’s disease Consortium, the Dutch Initiative on Crohn and Colitis (ICC) and the Initiative on Crohn and Colitis - Surgery (ICC-S). Munster LJ, et al. Among authors: hart al. J Crohns Colitis. 2025 Jan 7:jjaf002. doi: 10.1093/ecco-jcc/jjaf002. Online ahead of print. J Crohns Colitis. 2025. PMID: 39777453
2,798 results