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Preclinical Characterization of a Next-Generation Brain Permeable, Paradox Breaker BRAF Inhibitor.
Wichmann J, Rynn C, Friess T, Petrig-Schaffland J, Kornacker M, Handl C, Emmenegger J, Eckmann J, Herting F, Frances N, Hunziker D, Krummenacher D, Rüttinger D, Ribeiro A, Bacac M, Brigo A, Hewings DS, Dummer R, Levesque MP, Schnetzler G, Martoglio B, Bischoff JR, Pettazzoni P. Wichmann J, et al. Among authors: frances n. Clin Cancer Res. 2022 Feb 15;28(4):770-780. doi: 10.1158/1078-0432.CCR-21-2761. Clin Cancer Res. 2022. PMID: 34782366
Predicting Tumor Killing and T-Cell Activation by T-Cell Bispecific Antibodies as a Function of Target Expression: Combining In Vitro Experiments with Systems Modeling.
Van De Vyver AJ, Weinzierl T, Eigenmann MJ, Frances N, Herter S, Buser RB, Somandin J, Diggelmann S, Limani F, Lehr T, Bacac M, Walz AC. Van De Vyver AJ, et al. Among authors: frances n. Mol Cancer Ther. 2021 Feb;20(2):357-366. doi: 10.1158/1535-7163.MCT-20-0269. Epub 2020 Dec 9. Mol Cancer Ther. 2021. PMID: 33298591
PKPD modeling of acquired resistance to anti-cancer drug treatment.
Eigenmann MJ, Frances N, Lavé T, Walz AC. Eigenmann MJ, et al. Among authors: frances n. J Pharmacokinet Pharmacodyn. 2017 Dec;44(6):617-630. doi: 10.1007/s10928-017-9553-x. Epub 2017 Oct 31. J Pharmacokinet Pharmacodyn. 2017. PMID: 29090407 Free PMC article.
A prognostic baseline blood biomarker and tumor growth kinetics integrated model in paclitaxel/platinum treated advanced non-small cell lung cancer patients.
Ojara FW, Henrich A, Frances N, Nassar YM, Huisinga W, Hartung N, Geiger K, Holdenrieder S, Joerger M, Kloft C. Ojara FW, et al. Among authors: frances n. CPT Pharmacometrics Syst Pharmacol. 2023 Nov;12(11):1714-1725. doi: 10.1002/psp4.12937. Epub 2023 Feb 27. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 36782356 Free PMC article.
24 results