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An aluminum hydroxide:CpG adjuvant enhances protection elicited by a SARS-CoV-2 receptor binding domain vaccine in aged mice.
Nanishi E, Borriello F, O'Meara TR, McGrath ME, Saito Y, Haupt RE, Seo HS, van Haren SD, Cavazzoni CB, Brook B, Barman S, Chen J, Diray-Arce J, Doss-Gollin S, De Leon M, Prevost-Reilly A, Chew K, Menon M, Song K, Xu AZ, Caradonna TM, Feldman J, Hauser BM, Schmidt AG, Sherman AC, Baden LR, Ernst RK, Dillen C, Weston SM, Johnson RM, Hammond HL, Mayer R, Burke A, Bottazzi ME, Hotez PJ, Strych U, Chang A, Yu J, Sage PT, Barouch DH, Dhe-Paganon S, Zanoni I, Ozonoff A, Frieman MB, Levy O, Dowling DJ. Nanishi E, et al. Among authors: van haren sd. Sci Transl Med. 2022 Jan 26;14(629):eabj5305. doi: 10.1126/scitranslmed.abj5305. Epub 2022 Jan 26. Sci Transl Med. 2022. PMID: 34783582 Free PMC article.
Soluble mediators regulating immunity in early life.
Pettengill MA, van Haren SD, Levy O. Pettengill MA, et al. Among authors: van haren sd. Front Immunol. 2014 Sep 24;5:457. doi: 10.3389/fimmu.2014.00457. eCollection 2014. Front Immunol. 2014. PMID: 25309541 Free PMC article. Review.
A Meningococcal Outer Membrane Vesicle Vaccine Incorporating Genetically Attenuated Endotoxin Dissociates Inflammation from Immunogenicity.
Dowling DJ, Sanders H, Cheng WK, Joshi S, Brightman S, Bergelson I, Pietrasanta C, van Haren SD, van Amsterdam S, Fernandez J, van den Dobbelsteen GP, Levy O. Dowling DJ, et al. Among authors: van amsterdam s, van den dobbelsteen gp, van haren sd. Front Immunol. 2016 Dec 8;7:562. doi: 10.3389/fimmu.2016.00562. eCollection 2016. Front Immunol. 2016. PMID: 28008331 Free PMC article.
Toll-like receptor 8 agonist nanoparticles mimic immunomodulating effects of the live BCG vaccine and enhance neonatal innate and adaptive immune responses.
Dowling DJ, Scott EA, Scheid A, Bergelson I, Joshi S, Pietrasanta C, Brightman S, Sanchez-Schmitz G, Van Haren SD, Ninković J, Kats D, Guiducci C, de Titta A, Bonner DK, Hirosue S, Swartz MA, Hubbell JA, Levy O. Dowling DJ, et al. Among authors: van haren sd. J Allergy Clin Immunol. 2017 Nov;140(5):1339-1350. doi: 10.1016/j.jaci.2016.12.985. Epub 2017 Mar 23. J Allergy Clin Immunol. 2017. PMID: 28343701 Free PMC article.
TLR7/8 adjuvant overcomes newborn hyporesponsiveness to pneumococcal conjugate vaccine at birth.
Dowling DJ, van Haren SD, Scheid A, Bergelson I, Kim D, Mancuso CJ, Foppen W, Ozonoff A, Fresh L, Theriot TB, Lackner AA, Fichorova RN, Smirnov D, Vasilakos JP, Beaurline JM, Tomai MA, Midkiff CC, Alvarez X, Blanchard JL, Gilbert MH, Aye PP, Levy O. Dowling DJ, et al. Among authors: van haren sd. JCI Insight. 2017 Mar 23;2(6):e91020. doi: 10.1172/jci.insight.91020. JCI Insight. 2017. PMID: 28352660 Free PMC article.
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