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PP2A is a therapeutically targetable driver of cell fate decisions via a c-Myc/p21 axis in human and murine acute myeloid leukemia.
Goswami S, Mani R, Nunes J, Chiang CL, Zapolnik K, Hu E, Frissora F, Mo X, Walker LA, Yan P, Bundschuh R, Beaver L, Devine R, Tsai YT, Ventura A, Xie Z, Chen M, Lapalombella R, Walker A, Mims A, Larkin K, Grieselhuber N, Bennett C, Phelps M, Hertlein E, Behbehani G, Vasu S, Byrd JC, Muthusamy N. Goswami S, et al. Among authors: vasu s. Blood. 2022 Mar 3;139(9):1340-1358. doi: 10.1182/blood.2020010344. Blood. 2022. PMID: 34788382 Free PMC article.
MicroRNAs activate natural killer cells through Toll-like receptor signaling.
He S, Chu J, Wu LC, Mao H, Peng Y, Alvarez-Breckenridge CA, Hughes T, Wei M, Zhang J, Yuan S, Sandhu S, Vasu S, Benson DM Jr, Hofmeister CC, He X, Ghoshal K, Devine SM, Caligiuri MA, Yu J. He S, et al. Among authors: vasu s. Blood. 2013 Jun 6;121(23):4663-71. doi: 10.1182/blood-2012-07-441360. Epub 2013 Apr 11. Blood. 2013. PMID: 23580661 Free PMC article.
Decitabine priming enhances the antileukemic effects of exportin 1 (XPO1) selective inhibitor selinexor in acute myeloid leukemia.
Ranganathan P, Yu X, Santhanam R, Hofstetter J, Walker A, Walsh K, Bhatnagar B, Klisovic R, Vasu S, Phelps MA, Devine S, Shacham S, Kauffman M, Marcucci G, Blum W, Garzon R. Ranganathan P, et al. Among authors: vasu s. Blood. 2015 Apr 23;125(17):2689-92. doi: 10.1182/blood-2014-10-607648. Epub 2015 Feb 25. Blood. 2015. PMID: 25716206 Free PMC article.
Granulocyte Colony-Stimulating Factor-Mobilized Allografts Contain Activated Immune Cell Subsets Associated with Risk of Acute and Chronic Graft-versus-Host Disease.
Vasu S, Geyer S, Bingman A, Auletta JJ, Jaglowski S, Elder P, O'Donnell LC, Bradbury H, Kitzler R, Andritsos L, Blum W, Klisovic R, Penza S, Efebera Y, Hofmeister C, Benson DM, Muthusamy N, Lozanski G, Devine SM. Vasu S, et al. Biol Blood Marrow Transplant. 2016 Apr;22(4):658-668. doi: 10.1016/j.bbmt.2015.12.015. Epub 2015 Dec 29. Biol Blood Marrow Transplant. 2016. PMID: 26743340 Free article.
Midostaurin, bortezomib and MEC in relapsed/refractory acute myeloid leukemia.
Walker AR, Wang H, Walsh K, Bhatnagar B, Vasu S, Garzon R, Canning R, Geyer S, Wu YZ, Devine SM, Klisovic R, Blum W, Marcucci G. Walker AR, et al. Among authors: vasu s. Leuk Lymphoma. 2016 Sep;57(9):2100-8. doi: 10.3109/10428194.2015.1135435. Epub 2016 Jan 19. Leuk Lymphoma. 2016. PMID: 26784138 Free PMC article.
Decitabine enhances anti-CD33 monoclonal antibody BI 836858-mediated natural killer ADCC against AML blasts.
Vasu S, He S, Cheney C, Gopalakrishnan B, Mani R, Lozanski G, Mo X, Groh V, Whitman SP, Konopitzky R, Kössl C, Bucci D, Lucas DM, Yu J, Caligiuri MA, Blum W, Adam PJ, Borges E, Rueter B, Heider KH, Marcucci G, Muthusamy N. Vasu S, et al. Blood. 2016 Jun 9;127(23):2879-89. doi: 10.1182/blood-2015-11-680546. Epub 2016 Mar 24. Blood. 2016. PMID: 27013443 Free PMC article.
MicroRNA-29b mediates altered innate immune development in acute leukemia.
Mundy-Bosse BL, Scoville SD, Chen L, McConnell K, Mao HC, Ahmed EH, Zorko N, Harvey S, Cole J, Zhang X, Costinean S, Croce CM, Larkin K, Byrd JC, Vasu S, Blum W, Yu J, Freud AG, Caligiuri MA. Mundy-Bosse BL, et al. Among authors: vasu s. J Clin Invest. 2016 Dec 1;126(12):4404-4416. doi: 10.1172/JCI85413. Epub 2016 Oct 24. J Clin Invest. 2016. PMID: 27775550 Free PMC article.
Interferon-γ Promotes Antibody-mediated Fratricide of Acute Myeloid Leukemia Cells.
Fatehchand K, McMichael EL, Reader BF, Fang H, Santhanam R, Gautam S, Elavazhagan S, Mehta P, Buteyn NJ, Merchand-Reyes G, Vasu S, Mo X, Benson DM Jr, Blachly JS, Carson WE 3rd, Byrd JC, Butchar JP, Tridandapani S. Fatehchand K, et al. Among authors: vasu s. J Biol Chem. 2016 Dec 2;291(49):25656-25666. doi: 10.1074/jbc.M116.753145. Epub 2016 Oct 25. J Biol Chem. 2016. PMID: 27780867 Free PMC article.
273 results