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Immunizations with diverse sarbecovirus receptor-binding domains elicit SARS-CoV-2 neutralizing antibodies against a conserved site of vulnerability.
Burnett DL, Jackson KJL, Langley DB, Aggrawal A, Stella AO, Johansen MD, Balachandran H, Lenthall H, Rouet R, Walker G, Saunders BM, Singh M, Li H, Henry JY, Jackson J, Stewart AG, Witthauer F, Spence MA, Hansbro NG, Jackson C, Schofield P, Milthorpe C, Martinello M, Schulz SR, Roth E, Kelleher A, Emery S, Britton WJ, Rawlinson WD, Karl R, Schäfer S, Winkler TH, Brink R, Bull RA, Hansbro PM, Jäck HM, Turville S, Christ D, Goodnow CC. Burnett DL, et al. Among authors: jackson c, jackson j, jackson kjl. Immunity. 2021 Dec 14;54(12):2908-2921.e6. doi: 10.1016/j.immuni.2021.10.019. Epub 2021 Oct 29. Immunity. 2021. PMID: 34788600 Free PMC article.
Human Antibody Bispecifics through Phage Display Selection.
Luthra A, Langley DB, Schofield P, Jackson J, Abdelatti M, Rouet R, Nevoltris D, Mazigi O, Crossett B, Christie M, Christ D. Luthra A, et al. Among authors: jackson j. Biochemistry. 2019 Apr 2;58(13):1701-1704. doi: 10.1021/acs.biochem.9b00037. Epub 2019 Mar 22. Biochemistry. 2019. PMID: 30900875
Conformational diversity facilitates antibody mutation trajectories and discrimination between foreign and self-antigens.
Burnett DL, Schofield P, Langley DB, Jackson J, Bourne K, Wilson E, Porebski BT, Buckle AM, Brink R, Goodnow CC, Christ D. Burnett DL, et al. Among authors: jackson j. Proc Natl Acad Sci U S A. 2020 Sep 8;117(36):22341-22350. doi: 10.1073/pnas.2005102117. Epub 2020 Aug 27. Proc Natl Acad Sci U S A. 2020. PMID: 32855302 Free PMC article.
Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1 antibodies.
Rouet R, Mazigi O, Walker GJ, Langley DB, Sobti M, Schofield P, Lenthall H, Jackson J, Ubiparipovic S, Henry JY, Abayasingam A, Burnett D, Kelleher A, Brink R, Bull RA, Turville S, Stewart AG, Goodnow CC, Rawlinson WD, Christ D. Rouet R, et al. Among authors: jackson j. MAbs. 2021 Jan-Dec;13(1):1922134. doi: 10.1080/19420862.2021.1922134. MAbs. 2021. PMID: 34024246 Free PMC article.
Platform for isolation and characterization of SARS-CoV-2 variants enables rapid characterization of Omicron in Australia.
Aggarwal A, Stella AO, Walker G, Akerman A, Esneau C, Milogiannakis V, Burnett DL, McAllery S, Silva MR, Lu Y, Foster CSP, Brilot F, Pillay A, Van Hal S, Mathivanan V, Fichter C, Kindinger A, Hoppe AC, Munier ML, Amatayakul-Chantler S, Roth N, Coppola G, Symonds GP, Schofield P, Jackson J, Lenthall H, Henry JY, Mazigi O, Jäck HM, Davenport MP, Darley DR, Matthews GV, Khoury DS, Cromer D, Goodnow CC, Christ D, Robosa R, Starck DJ, Bartlett NW, Rawlinson WD, Kelleher AD, Turville SG. Aggarwal A, et al. Among authors: jackson j. Nat Microbiol. 2022 Jun;7(6):896-908. doi: 10.1038/s41564-022-01135-7. Epub 2022 May 30. Nat Microbiol. 2022. PMID: 35637329 Free PMC article.
Genetic and structural basis of the human anti-α-galactosyl antibody response.
Langley DB, Schofield P, Nevoltris D, Jackson J, Jackson KJL, Peters TJ, Burk M, Matthews JM, Basten A, Goodnow CC, van Nunen S, Reed JH, Christ D. Langley DB, et al. Among authors: jackson j, jackson kjl. Proc Natl Acad Sci U S A. 2022 Jul 12;119(28):e2123212119. doi: 10.1073/pnas.2123212119. Epub 2022 Jul 8. Proc Natl Acad Sci U S A. 2022. PMID: 35867757 Free PMC article.
6,099 results