Gumpper RH - Search Results

1

Structure, function and pharmacology of human itch GPCRs.

Cao C, Kang HJ, Singh I, Chen H, Zhang C, Ye W, Hayes BW, Liu J, Gumpper RH, Bender BJ, Slocum ST, Krumm BE, Lansu K, McCorvy JD, Kroeze WK, English JG, DiBerto JF, Olsen RHJ, Huang XP, Zhang S, Liu Y, Kim K, Karpiak J, Jan LY, Abraham SN, Jin J, Shoichet BK, Fay JF, Roth BL. Cao C, et al. Among authors: gumpper rh. Nature. 2021 Dec;600(7887):170-175. doi: 10.1038/s41586-021-04126-6. Epub 2021 Nov 17. Nature. 2021. PMID: 34789874 Free PMC article.

2

G-Protein Peptidomimetics Stabilize GPCR Active State Conformations.

Gumpper RH, Roth BL. Gumpper RH, et al. Trends Pharmacol Sci. 2021 Jun;42(6):429-430. doi: 10.1016/j.tips.2021.03.009. Epub 2021 Apr 16. Trends Pharmacol Sci. 2021. PMID: 33875228

3

Molecular insights into the regulation of constitutive activity by RNA editing of 5HT_2C serotonin receptors.

Gumpper RH, Fay JF, Roth BL. Gumpper RH, et al. Cell Rep. 2022 Aug 16;40(7):111211. doi: 10.1016/j.celrep.2022.111211. Cell Rep. 2022. PMID: 35977511 Free PMC article.

4

Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD.

Cao C, Barros-Álvarez X, Zhang S, Kim K, Dämgen MA, Panova O, Suomivuori CM, Fay JF, Zhong X, Krumm BE, Gumpper RH, Seven AB, Robertson MJ, Krogan NJ, Hüttenhain R, Nichols DE, Dror RO, Skiniotis G, Roth BL. Cao C, et al. Among authors: gumpper rh. Neuron. 2022 Oct 5;110(19):3154-3167.e7. doi: 10.1016/j.neuron.2022.08.006. Epub 2022 Sep 9. Neuron. 2022. PMID: 36087581 Free PMC article.

5

Ligand recognition and allosteric modulation of the human MRGPRX1 receptor.

Liu Y, Cao C, Huang XP, Gumpper RH, Rachman MM, Shih SL, Krumm BE, Zhang S, Shoichet BK, Fay JF, Roth BL. Liu Y, et al. Among authors: gumpper rh. Nat Chem Biol. 2023 Apr;19(4):416-422. doi: 10.1038/s41589-022-01173-6. Epub 2022 Oct 27. Nat Chem Biol. 2023. PMID: 36302898

6

Molecular basis for selective activation of DREADD-based chemogenetics.

Zhang S, Gumpper RH, Huang XP, Liu Y, Krumm BE, Cao C, Fay JF, Roth BL. Zhang S, et al. Among authors: gumpper rh. Nature. 2022 Dec;612(7939):354-362. doi: 10.1038/s41586-022-05489-0. Epub 2022 Nov 30. Nature. 2022. PMID: 36450989

7

Hemoglobin crystals immersed in liquid oxygen reveal diffusion channels.

Terrell JR, Gumpper RH, Luo M. Terrell JR, et al. Among authors: gumpper rh. Biochem Biophys Res Commun. 2018 Jan 8;495(2):1858-1863. doi: 10.1016/j.bbrc.2017.12.038. Epub 2017 Dec 12. Biochem Biophys Res Commun. 2018. PMID: 29246762

8

High-resolution structure of the Influenza A virus PB2cap binding domain illuminates the changes induced by ligand binding.

Constantinides A, Gumpper R, Severin C, Luo M. Constantinides A, et al. Acta Crystallogr F Struct Biol Commun. 2018 Mar 1;74(Pt 3):122-127. doi: 10.1107/S2053230X18000894. Epub 2018 Feb 26. Acta Crystallogr F Struct Biol Commun. 2018. PMID: 29497014 Free PMC article.

9

An Iron Reservoir to the Catalytic Metal: THE RUBREDOXIN IRON IN AN EXTRADIOL DIOXYGENASE.

Liu F, Geng J, Gumpper RH, Barman A, Davis I, Ozarowski A, Hamelberg D, Liu A. Liu F, et al. Among authors: gumpper rh. J Biol Chem. 2015 Jun 19;290(25):15621-15634. doi: 10.1074/jbc.M115.650259. Epub 2015 Apr 27. J Biol Chem. 2015. PMID: 25918158 Free PMC article.

10

A Polyamide Inhibits Replication of Vesicular Stomatitis Virus by Targeting RNA in the Nucleocapsid.

Gumpper RH, Li W, Castañeda CH, Scuderi MJ, Bashkin JK, Luo M. Gumpper RH, et al. J Virol. 2018 Mar 28;92(8):e00146-18. doi: 10.1128/JVI.00146-18. Print 2018 Apr 15. J Virol. 2018. PMID: 29437970 Free PMC article.

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