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WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification.
Coombs GS, Yu J, Canning CA, Veltri CA, Covey TM, Cheong JK, Utomo V, Banerjee N, Zhang ZH, Jadulco RC, Concepcion GP, Bugni TS, Harper MK, Mihalek I, Jones CM, Ireland CM, Virshup DM. Coombs GS, et al. Among authors: yu j. J Cell Sci. 2010 Oct 1;123(Pt 19):3357-67. doi: 10.1242/jcs.072132. Epub 2010 Sep 7. J Cell Sci. 2010. PMID: 20826466 Free PMC article.
Updating the Wnt pathways.
Yu J, Virshup DM. Yu J, et al. Biosci Rep. 2014 Oct 17;34(5):e00142. doi: 10.1042/BSR20140119. Biosci Rep. 2014. PMID: 25208913 Free PMC article.
Analysis of wntless (WLS) expression in gastric, ovarian, and breast cancers reveals a strong association with HER2 overexpression.
Stewart J, James J, McCluggage GW, McQuaid S, Arthur K, Boyle D, Mullan P, McArt D, Yan B, Irwin G, Harkin DP, Zhengdeng L, Ong CW, Yu J, Virshup DM, Salto-Tellez M. Stewart J, et al. Among authors: yu j. Mod Pathol. 2015 Mar;28(3):428-36. doi: 10.1038/modpathol.2014.114. Epub 2014 Sep 26. Mod Pathol. 2015. PMID: 25258105 Free article.
Wnt traffic from endoplasmic reticulum to filopodia.
Moti N, Yu J, Boncompain G, Perez F, Virshup DM. Moti N, et al. Among authors: yu j. PLoS One. 2019 Feb 22;14(2):e0212711. doi: 10.1371/journal.pone.0212711. eCollection 2019. PLoS One. 2019. PMID: 30794657 Free PMC article.
Wnts and the hallmarks of cancer.
Zhong Z, Yu J, Virshup DM, Madan B. Zhong Z, et al. Among authors: yu j. Cancer Metastasis Rev. 2020 Sep;39(3):625-645. doi: 10.1007/s10555-020-09887-6. Cancer Metastasis Rev. 2020. PMID: 32385713 Review.
Structural Basis of WLS/Evi-Mediated Wnt Transport and Secretion.
Nygaard R, Yu J, Kim J, Ross DR, Parisi G, Clarke OB, Virshup DM, Mancia F. Nygaard R, et al. Among authors: yu j. Cell. 2021 Jan 7;184(1):194-206.e14. doi: 10.1016/j.cell.2020.11.038. Epub 2020 Dec 23. Cell. 2021. PMID: 33357447 Free PMC article.
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