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The S-adenosylmethionine analog sinefungin inhibits the trimethylguanosine synthase TGS1 to promote telomerase activity and telomere lengthening.
Galati A, Scatolini L, Micheli E, Bavasso F, Cicconi A, Maccallini P, Chen L, Roake CM, Schoeftner S, Artandi SE, Gatti M, Cacchione S, Raffa GD. Galati A, et al. Among authors: artandi se. FEBS Lett. 2022 Jan;596(1):42-52. doi: 10.1002/1873-3468.14240. Epub 2021 Dec 5. FEBS Lett. 2022. PMID: 34817067 Free article.
DNA repair: Telomere-lengthening mechanism revealed.
Roake CM, Artandi SE. Roake CM, et al. Among authors: artandi se. Nature. 2016 Nov 3;539(7627):35-36. doi: 10.1038/nature19483. Epub 2016 Oct 19. Nature. 2016. PMID: 27760112 No abstract available.
An Activity Switch in Human Telomerase Based on RNA Conformation and Shaped by TCAB1.
Chen L, Roake CM, Freund A, Batista PJ, Tian S, Yin YA, Gajera CR, Lin S, Lee B, Pech MF, Venteicher AS, Das R, Chang HY, Artandi SE. Chen L, et al. Among authors: artandi se. Cell. 2018 Jun 28;174(1):218-230.e13. doi: 10.1016/j.cell.2018.04.039. Epub 2018 May 24. Cell. 2018. PMID: 29804836 Free PMC article.
Disruption of Telomerase RNA Maturation Kinetics Precipitates Disease.
Roake CM, Chen L, Chakravarthy AL, Ferrell JE Jr, Raffa GD, Artandi SE. Roake CM, et al. Among authors: artandi se. Mol Cell. 2019 May 16;74(4):688-700.e3. doi: 10.1016/j.molcel.2019.02.033. Epub 2019 Mar 28. Mol Cell. 2019. PMID: 30930056 Free PMC article.
HiChIRP reveals RNA-associated chromosome conformation.
Mumbach MR, Granja JM, Flynn RA, Roake CM, Satpathy AT, Rubin AJ, Qi Y, Jiang Z, Shams S, Louie BH, Guo JK, Gennert DG, Corces MR, Khavari PA, Atianand MK, Artandi SE, Fitzgerald KA, Greenleaf WJ, Chang HY. Mumbach MR, et al. Among authors: artandi se. Nat Methods. 2019 Jun;16(6):489-492. doi: 10.1038/s41592-019-0407-x. Epub 2019 May 27. Nat Methods. 2019. PMID: 31133759 Free PMC article.
86 results