Rock CO - Search Results

1

Oleate Hydratase (OhyA) Is a Virulence Determinant in Staphylococcus aureus.

Radka CD, Batte JL, Frank MW, Rosch JW, Rock CO. Radka CD, et al. Among authors: rock co. Microbiol Spectr. 2021 Dec 22;9(3):e0154621. doi: 10.1128/Spectrum.01546-21. Epub 2021 Nov 24. Microbiol Spectr. 2021. PMID: 34817231 Free PMC article.

2

Acyl carrier protein is a cellular target for the antibacterial action of the pantothenamide class of pantothenate antimetabolites.

Zhang YM, Frank MW, Virga KG, Lee RE, Rock CO, Jackowski S. Zhang YM, et al. Among authors: rock co. J Biol Chem. 2004 Dec 3;279(49):50969-75. doi: 10.1074/jbc.M409607200. Epub 2004 Sep 30. J Biol Chem. 2004. PMID: 15459190 Free article.

3

Serum opacity factor, a streptococcal virulence factor that binds to apolipoproteins A-I and A-II and disrupts high density lipoprotein structure.

Courtney HS, Zhang YM, Frank MW, Rock CO. Courtney HS, et al. Among authors: rock co. J Biol Chem. 2006 Mar 3;281(9):5515-21. doi: 10.1074/jbc.M512538200. Epub 2006 Jan 3. J Biol Chem. 2006. PMID: 16407233 Free article.

4

A Pseudomonas aeruginosa transcription factor that senses fatty acid structure.

Zhang YM, Zhu K, Frank MW, Rock CO. Zhang YM, et al. Among authors: rock co. Mol Microbiol. 2007 Nov;66(3):622-32. doi: 10.1111/j.1365-2958.2007.05934.x. Epub 2007 Sep 18. Mol Microbiol. 2007. PMID: 17877713 Free article.

5

PqsD is responsible for the synthesis of 2,4-dihydroxyquinoline, an extracellular metabolite produced by Pseudomonas aeruginosa.

Zhang YM, Frank MW, Zhu K, Mayasundari A, Rock CO. Zhang YM, et al. Among authors: rock co. J Biol Chem. 2008 Oct 24;283(43):28788-94. doi: 10.1074/jbc.M804555200. Epub 2008 Aug 26. J Biol Chem. 2008. PMID: 18728009 Free PMC article.

6

Elimination of the CDP-ethanolamine pathway disrupts hepatic lipid homeostasis.

Leonardi R, Frank MW, Jackson PD, Rock CO, Jackowski S. Leonardi R, et al. Among authors: rock co. J Biol Chem. 2009 Oct 2;284(40):27077-89. doi: 10.1074/jbc.M109.031336. Epub 2009 Aug 7. J Biol Chem. 2009. PMID: 19666474 Free PMC article.

7

Metabolic basis for the differential susceptibility of Gram-positive pathogens to fatty acid synthesis inhibitors.

Parsons JB, Frank MW, Subramanian C, Saenkham P, Rock CO. Parsons JB, et al. Among authors: rock co. Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15378-83. doi: 10.1073/pnas.1109208108. Epub 2011 Aug 29. Proc Natl Acad Sci U S A. 2011. PMID: 21876172 Free PMC article.

8

Membrane disruption by antimicrobial fatty acids releases low-molecular-weight proteins from Staphylococcus aureus.

Parsons JB, Yao J, Frank MW, Jackson P, Rock CO. Parsons JB, et al. Among authors: rock co. J Bacteriol. 2012 Oct;194(19):5294-304. doi: 10.1128/JB.00743-12. Epub 2012 Jul 27. J Bacteriol. 2012. PMID: 22843840 Free PMC article.

9

Perturbation of Staphylococcus aureus gene expression by the enoyl-acyl carrier protein reductase inhibitor AFN-1252.

Parsons JB, Kukula M, Jackson P, Pulse M, Simecka JW, Valtierra D, Weiss WJ, Kaplan N, Rock CO. Parsons JB, et al. Among authors: rock co. Antimicrob Agents Chemother. 2013 May;57(5):2182-90. doi: 10.1128/AAC.02307-12. Epub 2013 Mar 4. Antimicrob Agents Chemother. 2013. PMID: 23459481 Free PMC article.

10

Staphylococcus aureus fatty acid auxotrophs do not proliferate in mice.

Parsons JB, Frank MW, Rosch JW, Rock CO. Parsons JB, et al. Among authors: rock co. Antimicrob Agents Chemother. 2013 Nov;57(11):5729-32. doi: 10.1128/AAC.01038-13. Epub 2013 Aug 26. Antimicrob Agents Chemother. 2013. PMID: 23979734 Free PMC article.

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