Yu LF - Search Results

1

Synthesis and antitumour evaluation of indole-2-carboxamides against paediatric brain cancer cells.

Alsayed SSR, Suri A, Bailey AW, Lane S, Werry EL, Huang CC, Yu LF, Kassiou M, Sredni ST, Gunosewoyo H. Alsayed SSR, et al. Among authors: yu lf. RSC Med Chem. 2021 Aug 23;12(11):1910-1925. doi: 10.1039/d1md00065a. eCollection 2021 Nov 17. RSC Med Chem. 2021. PMID: 34825187 Free PMC article.

2

From α4β2 Nicotinic Ligands to the Discovery of σ1 Receptor Ligands: Pharmacophore Analysis and Rational Design.

Yu LF, Zhang HK, Gunosewoyo H, Kozikowski AP. Yu LF, et al. ACS Med Chem Lett. 2012 Dec 13;3(12):1054-1058. doi: 10.1021/ml3002715. ACS Med Chem Lett. 2012. PMID: 23641311 Free PMC article.

3

Development of Novel Alkoxyisoxazoles as Sigma-1 Receptor Antagonists with Antinociceptive Efficacy.

Sun H, Shi M, Zhang W, Zheng YM, Xu YZ, Shi JJ, Liu T, Gunosewoyo H, Pang T, Gao ZB, Yang F, Tang J, Yu LF. Sun H, et al. Among authors: yu lf. J Med Chem. 2016 Jul 14;59(13):6329-43. doi: 10.1021/acs.jmedchem.6b00571. Epub 2016 Jun 30. J Med Chem. 2016. PMID: 27309376

4

Synthesis and biological evaluation of novel hybrids of highly potent and selective α4β2-Nicotinic acetylcholine receptor (nAChR) partial agonists.

Zhang HK, Eaton JB, Fedolak A, Gunosewoyo H, Onajole OK, Brunner D, Lukas RJ, Yu LF, Kozikowski AP. Zhang HK, et al. Among authors: yu lf. Eur J Med Chem. 2016 Nov 29;124:689-697. doi: 10.1016/j.ejmech.2016.09.016. Epub 2016 Sep 9. Eur J Med Chem. 2016. PMID: 27639361 Free PMC article.

5

Kinase targets in CNS drug discovery.

Gunosewoyo H, Yu L, Munoz L, Kassiou M. Gunosewoyo H, et al. Future Med Chem. 2017 Mar;9(3):303-314. doi: 10.4155/fmc-2016-0214. Epub 2017 Feb 8. Future Med Chem. 2017. PMID: 28176536

6

Amidoalkylindoles as Potent and Selective Cannabinoid Type 2 Receptor Agonists with in Vivo Efficacy in a Mouse Model of Multiple Sclerosis.

Shi Y, Duan YH, Ji YY, Wang ZL, Wu YR, Gunosewoyo H, Xie XY, Chen JZ, Yang F, Li J, Tang J, Xie X, Yu LF. Shi Y, et al. Among authors: yu lf. J Med Chem. 2017 Aug 24;60(16):7067-7083. doi: 10.1021/acs.jmedchem.7b00724. Epub 2017 Aug 3. J Med Chem. 2017. PMID: 28726401

7

Tying up tranylcypromine: Novel selective histone lysine specific demethylase 1 (LSD1) inhibitors.

Ji YY, Lin SD, Wang YJ, Su MB, Zhang W, Gunosewoyo H, Yang F, Li J, Tang J, Zhou YB, Yu LF. Ji YY, et al. Among authors: yu lf. Eur J Med Chem. 2017 Dec 1;141:101-112. doi: 10.1016/j.ejmech.2017.09.073. Epub 2017 Oct 3. Eur J Med Chem. 2017. PMID: 29031059

8

Identification of Novel Coumestan Derivatives as Polyketide Synthase 13 Inhibitors against Mycobacterium tuberculosis.

Zhang W, Lun S, Wang SH, Jiang XW, Yang F, Tang J, Manson AL, Earl AM, Gunosewoyo H, Bishai WR, Yu LF. Zhang W, et al. Among authors: yu lf. J Med Chem. 2018 Feb 8;61(3):791-803. doi: 10.1021/acs.jmedchem.7b01319. Epub 2018 Jan 29. J Med Chem. 2018. PMID: 29328655

9

Identification of Novel Coumestan Derivatives as Polyketide Synthase 13 Inhibitors against Mycobacterium tuberculosis. Part II.

Zhang W, Lun S, Liu LL, Xiao S, Duan G, Gunosewoyo H, Yang F, Tang J, Bishai WR, Yu LF. Zhang W, et al. Among authors: yu lf. J Med Chem. 2019 Apr 11;62(7):3575-3589. doi: 10.1021/acs.jmedchem.9b00010. Epub 2019 Mar 27. J Med Chem. 2019. PMID: 30875203

10

Introducing nitrogen atoms to amidoalkylindoles: potent and selective cannabinoid type 2 receptor agonists with improved aqueous solubility.

Ji YY, Wang ZL, Pei FN, Shi JJ, Li JJ, Gunosewoyo H, Yang F, Tang J, Xie X, Yu LF. Ji YY, et al. Among authors: yu lf. Medchemcomm. 2019 Nov 18;10(12):2131-2139. doi: 10.1039/c9md00411d. eCollection 2019 Dec 1. Medchemcomm. 2019. PMID: 32904145 Free PMC article.

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