Pitman MR - Search Results

1

Resensitising proteasome inhibitor-resistant myeloma with sphingosine kinase 2 inhibition.

Bennett MK, Li M, Tea MN, Pitman MR, Toubia J, Wang PP, Anderson D, Creek DJ, Orlowski RZ, Gliddon BL, Powell JA, Wallington-Beddoe CT, Pitson SM. Bennett MK, et al. Among authors: pitman mr. Neoplasia. 2022 Jan;24(1):1-11. doi: 10.1016/j.neo.2021.11.009. Epub 2021 Nov 23. Neoplasia. 2022. PMID: 34826777 Free PMC article.

2

Inhibitors of the sphingosine kinase pathway as potential therapeutics.

Pitman MR, Pitson SM. Pitman MR, et al. Curr Cancer Drug Targets. 2010 Jun;10(4):354-67. doi: 10.2174/156800910791208599. Curr Cancer Drug Targets. 2010. PMID: 20370685 Review.

3

A critical role for the protein phosphatase 2A B'α regulatory subunit in dephosphorylation of sphingosine kinase 1.

Pitman MR, Barr RK, Gliddon BL, Magarey AM, Moretti PA, Pitson SM. Pitman MR, et al. Int J Biochem Cell Biol. 2011 Mar;43(3):342-7. doi: 10.1016/j.biocel.2010.11.001. Epub 2010 Nov 11. Int J Biochem Cell Biol. 2011. PMID: 21075214

4

Isoform-selective assays for sphingosine kinase activity.

Pitman MR, Pham DH, Pitson SM. Pitman MR, et al. Methods Mol Biol. 2012;874:21-31. doi: 10.1007/978-1-61779-800-9_2. Methods Mol Biol. 2012. PMID: 22528436

5

A selective ATP-competitive sphingosine kinase inhibitor demonstrates anti-cancer properties.

Pitman MR, Powell JA, Coolen C, Moretti PA, Zebol JR, Pham DH, Finnie JW, Don AS, Ebert LM, Bonder CS, Gliddon BL, Pitson SM. Pitman MR, et al. Oncotarget. 2015 Mar 30;6(9):7065-83. doi: 10.18632/oncotarget.3178. Oncotarget. 2015. PMID: 25788259 Free PMC article.

6

From Sphingosine Kinase to Dihydroceramide Desaturase: A Structure-Activity Relationship (SAR) Study of the Enzyme Inhibitory and Anticancer Activity of 4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol (SKI-II).

Aurelio L, Scullino CV, Pitman MR, Sexton A, Oliver V, Davies L, Rebello RJ, Furic L, Creek DJ, Pitson SM, Flynn BL. Aurelio L, et al. Among authors: pitman mr. J Med Chem. 2016 Feb 11;59(3):965-84. doi: 10.1021/acs.jmedchem.5b01439. Epub 2016 Feb 3. J Med Chem. 2016. PMID: 26780304

7

Proteasomal degradation of sphingosine kinase 1 and inhibition of dihydroceramide desaturase by the sphingosine kinase inhibitors, SKi or ABC294640, induces growth arrest in androgen-independent LNCaP-AI prostate cancer cells.

McNaughton M, Pitman M, Pitson SM, Pyne NJ, Pyne S. McNaughton M, et al. Oncotarget. 2016 Mar 29;7(13):16663-75. doi: 10.18632/oncotarget.7693. Oncotarget. 2016. PMID: 26934645 Free PMC article.

8

Topical Application of Fingolimod Perturbs Cutaneous Inflammation.

Sun WY, Dimasi DP, Pitman MR, Zhuang Y, Heddle R, Pitson SM, Grimbaldeston MA, Bonder CS. Sun WY, et al. Among authors: pitman mr. J Immunol. 2016 May 1;196(9):3854-64. doi: 10.4049/jimmunol.1501510. Epub 2016 Mar 21. J Immunol. 2016. PMID: 27001955

9

Recent advances in the development of sphingosine kinase inhibitors.

Pitman MR, Costabile M, Pitson SM. Pitman MR, et al. Cell Signal. 2016 Sep;28(9):1349-1363. doi: 10.1016/j.cellsig.2016.06.007. Epub 2016 Jun 11. Cell Signal. 2016. PMID: 27297359 Review.

10

An oncogenic role for sphingosine kinase 2.

Neubauer HA, Pham DH, Zebol JR, Moretti PA, Peterson AL, Leclercq TM, Chan H, Powell JA, Pitman MR, Samuel MS, Bonder CS, Creek DJ, Gliddon BL, Pitson SM. Neubauer HA, et al. Among authors: pitman mr. Oncotarget. 2016 Oct 4;7(40):64886-64899. doi: 10.18632/oncotarget.11714. Oncotarget. 2016. PMID: 27588496 Free PMC article.

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