Roper RJ - Search Results

1

Skeletal Deficits in Male and Female down Syndrome Model Mice Arise Independent of Normalized Dyrk1a Expression in Osteoblasts.

Thomas JR, Sloan K, Cave K, Wallace JM, Roper RJ. Thomas JR, et al. Among authors: roper rj. Genes (Basel). 2021 Oct 28;12(11):1729. doi: 10.3390/genes12111729. Genes (Basel). 2021. PMID: 34828335 Free PMC article.

2

Embryonic and not maternal trisomy causes developmental attenuation in the Ts65Dn mouse model for Down syndrome.

Blazek JD, Billingsley CN, Newbauer A, Roper RJ. Blazek JD, et al. Among authors: roper rj. Dev Dyn. 2010 Jun;239(6):1645-53. doi: 10.1002/dvdy.22295. Dev Dyn. 2010. PMID: 20503361 Free article.

3

Disruption of bone development and homeostasis by trisomy in Ts65Dn Down syndrome mice.

Blazek JD, Gaddy A, Meyer R, Roper RJ, Li J. Blazek JD, et al. Among authors: roper rj. Bone. 2011 Feb;48(2):275-80. doi: 10.1016/j.bone.2010.09.028. Epub 2010 Sep 24. Bone. 2011. PMID: 20870049 Free PMC article.

4

Trisomic and allelic differences influence phenotypic variability during development of Down syndrome mice.

Deitz SL, Roper RJ. Deitz SL, et al. Among authors: roper rj. Genetics. 2011 Dec;189(4):1487-95. doi: 10.1534/genetics.111.131391. Epub 2011 Sep 16. Genetics. 2011. PMID: 21926299 Free PMC article.

5

Commonality in Down and fetal alcohol syndromes.

Solzak JP, Liang Y, Zhou FC, Roper RJ. Solzak JP, et al. Among authors: roper rj. Birth Defects Res A Clin Mol Teratol. 2013 Apr;97(4):187-97. doi: 10.1002/bdra.23129. Epub 2013 Apr 3. Birth Defects Res A Clin Mol Teratol. 2013. PMID: 23554291 Free PMC article.

6

Non-trisomic homeobox gene expression during craniofacial development in the Ts65Dn mouse model of Down syndrome.

Billingsley CN, Allen JR, Baumann DD, Deitz SL, Blazek JD, Newbauer A, Darrah A, Long BC, Young B, Clement M, Doerge RW, Roper RJ. Billingsley CN, et al. Among authors: roper rj. Am J Med Genet A. 2013 Aug;161A(8):1866-74. doi: 10.1002/ajmg.a.36006. Epub 2013 Jul 10. Am J Med Genet A. 2013. PMID: 23843306 Free PMC article.

7

Abnormal mineralization of the Ts65Dn Down syndrome mouse appendicular skeleton begins during embryonic development in a Dyrk1a-independent manner.

Blazek JD, Malik AM, Tischbein M, Arbones ML, Moore CS, Roper RJ. Blazek JD, et al. Among authors: roper rj. Mech Dev. 2015 May;136:133-42. doi: 10.1016/j.mod.2014.12.004. Epub 2014 Dec 30. Mech Dev. 2015. PMID: 25556111 Free article.

8

Rescue of the abnormal skeletal phenotype in Ts65Dn Down syndrome mice using genetic and therapeutic modulation of trisomic Dyrk1a.

Blazek JD, Abeysekera I, Li J, Roper RJ. Blazek JD, et al. Among authors: roper rj. Hum Mol Genet. 2015 Oct 15;24(20):5687-96. doi: 10.1093/hmg/ddv284. Epub 2015 Jul 23. Hum Mol Genet. 2015. PMID: 26206885 Free article.

9

Low dose EGCG treatment beginning in adolescence does not improve cognitive impairment in a Down syndrome mouse model.

Stringer M, Abeysekera I, Dria KJ, Roper RJ, Goodlett CR. Stringer M, et al. Among authors: roper rj. Pharmacol Biochem Behav. 2015 Nov;138:70-9. doi: 10.1016/j.pbb.2015.09.002. Epub 2015 Sep 10. Pharmacol Biochem Behav. 2015. PMID: 26363314 Free article.

10

Differential effects of Epigallocatechin-3-gallate containing supplements on correcting skeletal defects in a Down syndrome mouse model.

Abeysekera I, Thomas J, Georgiadis TM, Berman AG, Hammond MA, Dria KJ, Wallace JM, Roper RJ. Abeysekera I, et al. Among authors: roper rj. Mol Nutr Food Res. 2016 Apr;60(4):717-726. doi: 10.1002/mnfr.201500781. Epub 2016 Feb 11. Mol Nutr Food Res. 2016. PMID: 26748562 Free PMC article.

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