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High-throughput mediation analysis of human proteome and metabolome identifies mediators of post-bariatric surgical diabetes control.
Dreyfuss JM, Yuchi Y, Dong X, Efthymiou V, Pan H, Simonson DC, Vernon A, Halperin F, Aryal P, Konkar A, Sebastian Y, Higgs BW, Grimsby J, Rondinone CM, Kasif S, Kahn BB, Foster K, Seeley R, Goldfine A, Djordjilović V, Patti ME. Dreyfuss JM, et al. Among authors: efthymiou v. Nat Commun. 2021 Nov 29;12(1):6951. doi: 10.1038/s41467-021-27289-2. Nat Commun. 2021. PMID: 34845204 Free PMC article. Clinical Trial.
Bromodomain Inhibition Reveals FGF15/19 As a Target of Epigenetic Regulation and Metabolic Control.
Kozuka C, Efthymiou V, Sales VM, Zhou L, Osataphan S, Yuchi Y, Chimene-Weiss J, Mulla C, Isganaitis E, Desmond J, Sanechika S, Kusuyama J, Goodyear L, Shi X, Gerszten RE, Aguayo-Mazzucato C, Carapeto P, Teixeira SD, Sandoval D, Alonso-Curbelo D, Wu L, Qi J, Patti ME. Kozuka C, et al. Among authors: efthymiou v. Diabetes. 2022 May 1;71(5):1023-1033. doi: 10.2337/db21-0574. Diabetes. 2022. PMID: 35100352 Free PMC article.
GPR180 is a component of TGFβ signalling that promotes thermogenic adipocyte function and mediates the metabolic effects of the adipocyte-secreted factor CTHRC1.
Balazova L, Balaz M, Horvath C, Horváth Á, Moser C, Kovanicova Z, Ghosh A, Ghoshdastider U, Efthymiou V, Kiehlmann E, Sun W, Dong H, Ding L, Amri EZ, Nuutila P, Virtanen KA, Niemi T, Ukropcova B, Ukropec J, Pelczar P, Lamla T, Hamilton B, Neubauer H, Wolfrum C. Balazova L, et al. Among authors: efthymiou v. Nat Commun. 2021 Dec 8;12(1):7144. doi: 10.1038/s41467-021-27442-x. Nat Commun. 2021. PMID: 34880217 Free PMC article.
SRF and MKL1 Independently Inhibit Brown Adipogenesis.
Rosenwald M, Efthymiou V, Opitz L, Wolfrum C. Rosenwald M, et al. Among authors: efthymiou v. PLoS One. 2017 Jan 26;12(1):e0170643. doi: 10.1371/journal.pone.0170643. eCollection 2017. PLoS One. 2017. PMID: 28125644 Free PMC article.
Cold-induced epigenetic programming of the sperm enhances brown adipose tissue activity in the offspring.
Sun W, Dong H, Becker AS, Dapito DH, Modica S, Grandl G, Opitz L, Efthymiou V, Straub LG, Sarker G, Balaz M, Balazova L, Perdikari A, Kiehlmann E, Bacanovic S, Zellweger C, Peleg-Raibstein D, Pelczar P, Reik W, Burger IA, von Meyenn F, Wolfrum C. Sun W, et al. Among authors: efthymiou v. Nat Med. 2018 Sep;24(9):1372-1383. doi: 10.1038/s41591-018-0102-y. Epub 2018 Jul 9. Nat Med. 2018. PMID: 29988127
Author Correction: Cold-induced epigenetic programming of the sperm enhances brown adipose tissue activity in the offspring.
Sun W, Dong H, Becker AS, Dapito DH, Modica S, Grandl G, Opitz L, Efthymiou V, Straub LG, Sarker G, Balaz M, Balazova L, Perdikari A, Kiehlmann E, Bacanovic S, Zellweger C, Peleg-Raibstein D, Pelczar P, Reik W, Burger IA, von Meyenn F, Wolfrum C. Sun W, et al. Among authors: efthymiou v. Nat Med. 2018 Nov;24(11):1776. doi: 10.1038/s41591-018-0162-z. Nat Med. 2018. PMID: 30087435
Publisher Correction: Cold-induced epigenetic programming of the sperm enhances brown adipose tissue activity in the offspring.
Sun W, Dong H, Becker AS, Dapito DH, Modica S, Grandl G, Opitz L, Efthymiou V, Straub LG, Sarker G, Balaz M, Balazova L, Perdikari A, Kiehlmann E, Bacanovic S, Zellweger C, Peleg-Raibstein D, Pelczar P, Reik W, Burger IA, von Meyenn F, Wolfrum C. Sun W, et al. Among authors: efthymiou v. Nat Med. 2018 Nov;24(11):1777. doi: 10.1038/s41591-018-0163-y. Nat Med. 2018. PMID: 30087436
Inhibition of Mevalonate Pathway Prevents Adipocyte Browning in Mice and Men by Affecting Protein Prenylation.
Balaz M, Becker AS, Balazova L, Straub L, Müller J, Gashi G, Maushart CI, Sun W, Dong H, Moser C, Horvath C, Efthymiou V, Rachamin Y, Modica S, Zellweger C, Bacanovic S, Stefanicka P, Varga L, Ukropcova B, Profant M, Opitz L, Amri EZ, Akula MK, Bergo M, Ukropec J, Falk C, Zamboni N, Betz MJ, Burger IA, Wolfrum C. Balaz M, et al. Among authors: efthymiou v. Cell Metab. 2019 Apr 2;29(4):901-916.e8. doi: 10.1016/j.cmet.2018.11.017. Epub 2018 Dec 20. Cell Metab. 2019. PMID: 30581121 Free article.
66 results