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Repeated Plasmodium falciparum infection in humans drives the clonal expansion of an adaptive γδ T cell repertoire.
von Borstel A, Chevour P, Arsovski D, Krol JMM, Howson LJ, Berry AA, Day CL, Ogongo P, Ernst JD, Nomicos EYH, Boddey JA, Giles EM, Rossjohn J, Traore B, Lyke KE, Williamson KC, Crompton PD, Davey MS. von Borstel A, et al. Among authors: giles em. Sci Transl Med. 2021 Dec;13(622):eabe7430. doi: 10.1126/scitranslmed.abe7430. Epub 2021 Dec 1. Sci Transl Med. 2021. PMID: 34851691 Free PMC article.
A class of γδ T cell receptors recognize the underside of the antigen-presenting molecule MR1.
Le Nours J, Gherardin NA, Ramarathinam SH, Awad W, Wiede F, Gully BS, Khandokar Y, Praveena T, Wubben JM, Sandow JJ, Webb AI, von Borstel A, Rice MT, Redmond SJ, Seneviratna R, Sandoval-Romero ML, Li S, Souter MNT, Eckle SBG, Corbett AJ, Reid HH, Liu L, Fairlie DP, Giles EM, Westall GP, Tothill RW, Davey MS, Berry R, Tiganis T, McCluskey J, Pellicci DG, Purcell AW, Uldrich AP, Godfrey DI, Rossjohn J. Le Nours J, et al. Among authors: giles em. Science. 2019 Dec 20;366(6472):1522-1527. doi: 10.1126/science.aav3900. Science. 2019. PMID: 31857486
Recognition of the antigen-presenting molecule MR1 by a Vδ3+ γδ T cell receptor.
Rice MT, von Borstel A, Chevour P, Awad W, Howson LJ, Littler DR, Gherardin NA, Le Nours J, Giles EM, Berry R, Godfrey DI, Davey MS, Rossjohn J, Gully BS. Rice MT, et al. Among authors: giles em. Proc Natl Acad Sci U S A. 2021 Dec 7;118(49):e2110288118. doi: 10.1073/pnas.2110288118. Proc Natl Acad Sci U S A. 2021. PMID: 34845016 Free PMC article.
36 results