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DNL343 is an investigational CNS penetrant eukaryotic initiation factor 2B activator that prevents and reverses the effects of neurodegeneration caused by the integrated stress response.
Yulyaningsih E, Suh JH, Fanok M, Chau R, Solanoy H, Takahashi R, Bakardjiev AI, Becerra I, Benitez NB, Chiu CL, Davis SS, Dowdle WE, Earr T, Estrada AA, Gill A, Ha C, Haddick PCG, Henne KR, Larhammar M, Leung AW, Maciuca R, Memarzadeh B, Nguyen HN, Nugent AA, Osipov M, Ran Y, Rebadulla K, Roche E, Sandmann T, Wang J, Lewcock JW, Scearce-Levie K, Kane LA, Sanchez PE. Yulyaningsih E, et al. Among authors: chiu cl. Elife. 2024 Sep 17;12:RP92173. doi: 10.7554/eLife.92173. Elife. 2024. PMID: 39287504 Free PMC article.
Low-level mosaic trisomy 14 at amniocentesis in a pregnancy associated with cytogenetic discrepancy between cultured amniocytes and uncultured amniocytes, positive non-invasive prenatal testing for trisomy 14, perinatal progressive decrease of the trisomy 14 cell line and a favorable fetal outcome.
Chen CP, Wu FT, Chang SY, Wu PS, Pan YT, Lee MS, Chiu CL, Wang W. Chen CP, et al. Among authors: chiu cl. Taiwan J Obstet Gynecol. 2024 Sep;63(5):755-758. doi: 10.1016/j.tjog.2024.07.006. Taiwan J Obstet Gynecol. 2024. PMID: 39266160 Free article.
Mosaic distal 13q duplication due to mosaic unbalanced translocation of 46,XY,der(14)t(13;14)(q32.2;p13)/46,XY at amniocentesis in a pregnancy associated with a favorable fetal outcome, perinatal progressive decrease of the aneuploid cell line and cytogenetic discrepancy between cultured amniocytes and uncultured amniocytes.
Chen CP, Wu FT, Chang SY, Wu PS, Pan YT, Lee CC, Chen WL, Lee MS, Chiu CL, Wang W. Chen CP, et al. Among authors: chiu cl. Taiwan J Obstet Gynecol. 2024 Sep;63(5):750-754. doi: 10.1016/j.tjog.2024.07.005. Taiwan J Obstet Gynecol. 2024. PMID: 39266159 Free article.
Establishing and Characterizing the Molecular Profiles, Cellular Features, and Clinical Utility of a Patient-Derived Xenograft Model Using Benign Prostatic Tissues.
Polasko AL, Zhang D, Ramraj A, Chiu CL, Garcia-Marques FJ, Bermudez A, Kapp K, Peterson E, Qiu Z, Pollack AS, Zhao H, Pollack JR, Pitteri SJ, Brooks JD. Polasko AL, et al. Among authors: chiu cl. Lab Invest. 2024 Oct;104(10):102129. doi: 10.1016/j.labinv.2024.102129. Epub 2024 Aug 31. Lab Invest. 2024. PMID: 39222914
167 results