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A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity.
Silva M, Kato Y, Melo MB, Phung I, Freeman BL, Li Z, Roh K, Van Wijnbergen JW, Watkins H, Enemuo CA, Hartwell BL, Chang JYH, Xiao S, Rodrigues KA, Cirelli KM, Li N, Haupt S, Aung A, Cossette B, Abraham W, Kataria S, Bastidas R, Bhiman J, Linde C, Bloom NI, Groschel B, Georgeson E, Phelps N, Thomas A, Bals J, Carnathan DG, Lingwood D, Burton DR, Alter G, Padera TP, Belcher AM, Schief WR, Silvestri G, Ruprecht RM, Crotty S, Irvine DJ. Silva M, et al. Among authors: padera tp. Sci Immunol. 2021 Dec 3;6(66):eabf1152. doi: 10.1126/sciimmunol.abf1152. Epub 2021 Dec 3. Sci Immunol. 2021. PMID: 34860581 Free PMC article.
Mapping the lymphatic system across body scales and expertise domains: A report from the 2021 National Heart, Lung, and Blood Institute workshop at the Boston Lymphatic Symposium.
Singhal D, Börner K, Chaikof EL, Detmar M, Hollmén M, Iliff JJ, Itkin M, Makinen T, Oliver G, Padera TP, Quardokus EM, Radtke AJ, Suami H, Weber GM, Rovira II, Muratoglu SC, Galis ZS. Singhal D, et al. Among authors: padera tp. Front Physiol. 2023 Feb 6;14:1099403. doi: 10.3389/fphys.2023.1099403. eCollection 2023. Front Physiol. 2023. PMID: 36814475 Free PMC article. Review.
Solid stress impairs lymphocyte infiltration into lymph-node metastases.
Jones D, Wang Z, Chen IX, Zhang S, Banerji R, Lei PJ, Zhou H, Xiao V, Kwong C, van Wijnbergen JWM, Pereira ER, Vakoc BJ, Huang P, Nia HT, Padera TP. Jones D, et al. Among authors: padera tp. Nat Biomed Eng. 2021 Dec;5(12):1426-1436. doi: 10.1038/s41551-021-00766-1. Epub 2021 Jul 19. Nat Biomed Eng. 2021. PMID: 34282290 Free PMC article.
Cancer cell plasticity and MHC-II-mediated immune tolerance promote breast cancer metastasis to lymph nodes.
Lei PJ, Pereira ER, Andersson P, Amoozgar Z, Van Wijnbergen JW, O'Melia MJ, Zhou H, Chatterjee S, Ho WW, Posada JM, Kumar AS, Morita S, Menzel L, Chung C, Ergin I, Jones D, Huang P, Beyaz S, Padera TP. Lei PJ, et al. Among authors: padera tp. J Exp Med. 2023 Sep 4;220(9):e20221847. doi: 10.1084/jem.20221847. Epub 2023 Jun 21. J Exp Med. 2023. PMID: 37341991 Free PMC article.
Lymphatic system regulation of anti-cancer immunity and metastasis.
Lei PJ, Fraser C, Jones D, Ubellacker JM, Padera TP. Lei PJ, et al. Among authors: padera tp. Front Immunol. 2024 Aug 15;15:1449291. doi: 10.3389/fimmu.2024.1449291. eCollection 2024. Front Immunol. 2024. PMID: 39211044 Free PMC article. Review.
Impaired lymphatic contraction associated with immunosuppression.
Liao S, Cheng G, Conner DA, Huang Y, Kucherlapati RS, Munn LL, Ruddle NH, Jain RK, Fukumura D, Padera TP. Liao S, et al. Among authors: padera tp. Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):18784-9. doi: 10.1073/pnas.1116152108. Epub 2011 Nov 7. Proc Natl Acad Sci U S A. 2011. PMID: 22065738 Free PMC article.
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