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A third SARS-CoV-2 spike vaccination improves neutralization of variants-of-concern.
Brinkkemper M, Brouwer PJM, Maisonnasse P, Grobben M, Caniels TG, Poniman M, Burger JA, Bontjer I, Oomen M, Bouhuijs JH, van der Linden CA, Villaudy J, van der Velden YU, Sliepen K, van Gils MJ, Le Grand R, Sanders RW. Brinkkemper M, et al. Among authors: van der velden yu, van gils mj, van der linden ca. NPJ Vaccines. 2021 Dec 3;6(1):146. doi: 10.1038/s41541-021-00411-7. NPJ Vaccines. 2021. PMID: 34862406 Free PMC article.
A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies.
Sanders RW, Derking R, Cupo A, Julien JP, Yasmeen A, de Val N, Kim HJ, Blattner C, de la Peña AT, Korzun J, Golabek M, de Los Reyes K, Ketas TJ, van Gils MJ, King CR, Wilson IA, Ward AB, Klasse PJ, Moore JP. Sanders RW, et al. Among authors: van gils mj. PLoS Pathog. 2013 Sep;9(9):e1003618. doi: 10.1371/journal.ppat.1003618. Epub 2013 Sep 19. PLoS Pathog. 2013. PMID: 24068931 Free PMC article.
Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers.
Blattner C, Lee JH, Sliepen K, Derking R, Falkowska E, de la Peña AT, Cupo A, Julien JP, van Gils M, Lee PS, Peng W, Paulson JC, Poignard P, Burton DR, Moore JP, Sanders RW, Wilson IA, Ward AB. Blattner C, et al. Immunity. 2014 May 15;40(5):669-80. doi: 10.1016/j.immuni.2014.04.008. Epub 2014 Apr 24. Immunity. 2014. PMID: 24768348 Free PMC article.
217 results