Weber IT - Search Results

1

Discovery of a new flavin N5-adduct in a tyrosine to phenylalanine variant of d-Arginine dehydrogenase.

Iyer A, Reis RAG, Agniswamy J, Weber IT, Gadda G. Iyer A, et al. Among authors: weber it. Arch Biochem Biophys. 2022 Jan 15;715:109100. doi: 10.1016/j.abb.2021.109100. Epub 2021 Dec 2. Arch Biochem Biophys. 2022. PMID: 34864048

2

Plasticity of S2-S4 specificity pockets of executioner caspase-7 revealed by structural and kinetic analysis.

Agniswamy J, Fang B, Weber IT. Agniswamy J, et al. Among authors: weber it. FEBS J. 2007 Sep;274(18):4752-65. doi: 10.1111/j.1742-4658.2007.05994.x. Epub 2007 Aug 14. FEBS J. 2007. PMID: 17697120 Free article.

3

Caught in the Act: the 1.5 A resolution crystal structures of the HIV-1 protease and the I54V mutant reveal a tetrahedral reaction intermediate.

Kovalevsky AY, Chumanevich AA, Liu F, Louis JM, Weber IT. Kovalevsky AY, et al. Among authors: weber it. Biochemistry. 2007 Dec 25;46(51):14854-64. doi: 10.1021/bi700822g. Epub 2007 Dec 4. Biochemistry. 2007. PMID: 18052235 Free PMC article.

4

Structural basis for executioner caspase recognition of P5 position in substrates.

Fu G, Chumanevich AA, Agniswamy J, Fang B, Harrison RW, Weber IT. Fu G, et al. Among authors: weber it. Apoptosis. 2008 Nov;13(11):1291-302. doi: 10.1007/s10495-008-0259-9. Apoptosis. 2008. PMID: 18780184 Free PMC article.

5

Caspases: structure-guided design of drugs to control cell death.

Weber IT, Fang B, Agniswamy J. Weber IT, et al. Mini Rev Med Chem. 2008 Oct;8(11):1154-62. doi: 10.2174/138955708785909899. Mini Rev Med Chem. 2008. PMID: 18855730 Review.

6

Caspase-3 binds diverse P4 residues in peptides as revealed by crystallography and structural modeling.

Fang B, Fu G, Agniswamy J, Harrison RW, Weber IT. Fang B, et al. Among authors: weber it. Apoptosis. 2009 May;14(5):741-52. doi: 10.1007/s10495-009-0333-y. Apoptosis. 2009. PMID: 19283487

7

Conformational similarity in the activation of caspase-3 and -7 revealed by the unliganded and inhibited structures of caspase-7.

Agniswamy J, Fang B, Weber IT. Agniswamy J, et al. Among authors: weber it. Apoptosis. 2009 Oct;14(10):1135-44. doi: 10.1007/s10495-009-0388-9. Apoptosis. 2009. PMID: 19655253

8

Role of valine 464 in the flavin oxidation reaction catalyzed by choline oxidase.

Finnegan S, Agniswamy J, Weber IT, Gadda G. Finnegan S, et al. Among authors: weber it. Biochemistry. 2010 Apr 6;49(13):2952-61. doi: 10.1021/bi902048c. Biochemistry. 2010. PMID: 20184377

9

Structural and kinetic studies on the Ser101Ala variant of choline oxidase: catalysis by compromise.

Finnegan S, Yuan H, Wang YF, Orville AM, Weber IT, Gadda G. Finnegan S, et al. Among authors: weber it. Arch Biochem Biophys. 2010 Sep 15;501(2):207-13. doi: 10.1016/j.abb.2010.06.014. Epub 2010 Jun 16. Arch Biochem Biophys. 2010. PMID: 20561507

10

Autocatalytic maturation, physical/chemical properties, and crystal structure of group N HIV-1 protease: relevance to drug resistance.

Sayer JM, Agniswamy J, Weber IT, Louis JM. Sayer JM, et al. Among authors: weber it. Protein Sci. 2010 Nov;19(11):2055-72. doi: 10.1002/pro.486. Protein Sci. 2010. PMID: 20737578 Free PMC article.

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