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The incidence of symptomatic osteonecrosis is similar between Japanese children and children in Western countries with acute lymphoblastic leukaemia treated with a Berlin-Frankfurt-Münster (BFM)95-based protocol.
Moriya K, Imamura T, Katayama S, Kaino A, Okamoto K, Yokoyama N, Uemura S, Kitazawa H, Sekimizu M, Hiramatsu H, Usami I, Ishida H, Hasegawa D, Hama A, Moriya-Saito A, Sato A, Sasahara Y, Suenobu S, Horibe K, Hara J; Japan Association of Childhood Leukemia Study Group (JACLS). Moriya K, et al. Among authors: kaino a. Br J Haematol. 2022 Mar;196(5):1257-1261. doi: 10.1111/bjh.17988. Epub 2021 Dec 8. Br J Haematol. 2022. PMID: 34879431