Chien N - Search Results

1

Use of anti-idiotypic antibodies to explore genetic mechanisms of production of anti-DNA antibodies.

Davidson A, Chien N, Frank L, Halpern R, Snapper S, Zupko K, Diamond B. Davidson A, et al. Among authors: chien n. Cell Immunol. 1986 Apr 15;99(1):44-52. doi: 10.1016/0008-8749(86)90214-5. Cell Immunol. 1986. PMID: 3489565

2

Somatic mutation alters affinity and specificity.

Diamond B, Chien N, Scharff M. Diamond B, et al. Among authors: chien n. Ann Inst Pasteur Immunol (1985). 1985 Mar-Apr;136C(2):267-71. doi: 10.1016/s0769-2625(85)80057-x. Ann Inst Pasteur Immunol (1985). 1985. PMID: 3890686 Review. No abstract available.

3

Effect of somatic mutation on antibody affinity and specificity.

Chien N, Giusti AM, Zack D, French D, Shin SU, Diamond B, Scharff MD. Chien N, et al. Mt Sinai J Med. 1986 Mar;53(3):181-6. Mt Sinai J Med. 1986. PMID: 2422550 No abstract available.

4

Impact of somatic mutation on the S107(T15) heavy-chain V region of antibodies reactive with self and nonself.

Behar SM, Chien NC, Corbet S, Diamond B, Getzoff ED, Lustgarten D, Roberts VA, Scharff MD, Shin SU. Behar SM, et al. Among authors: chien nc. Cold Spring Harb Symp Quant Biol. 1989;54 Pt 2:921-31. doi: 10.1101/sqb.1989.054.01.107. Cold Spring Harb Symp Quant Biol. 1989. PMID: 2518013 No abstract available.

5

Significant structural and functional change of an antigen-binding site by a distant amino acid substitution: proposal of a structural mechanism.

Chien NC, Roberts VA, Giusti AM, Scharff MD, Getzoff ED. Chien NC, et al. Proc Natl Acad Sci U S A. 1989 Jul;86(14):5532-6. doi: 10.1073/pnas.86.14.5532. Proc Natl Acad Sci U S A. 1989. PMID: 2748602 Free PMC article.

6

Somatic diversification of S107 from an antiphosphocholine to an anti-DNA autoantibody is due to a single base change in its heavy chain variable region.

Giusti AM, Chien NC, Zack DJ, Shin SU, Scharff MD. Giusti AM, et al. Among authors: chien nc. Proc Natl Acad Sci U S A. 1987 May;84(9):2926-30. doi: 10.1073/pnas.84.9.2926. Proc Natl Acad Sci U S A. 1987. PMID: 3106981 Free PMC article.

7

Point mutations cause the somatic diversification of IgM and IgG2a antiphosphorylcholine antibodies.

Chien NC, Pollock RR, Desaymard C, Scharff MD. Chien NC, et al. J Exp Med. 1988 Mar 1;167(3):954-73. doi: 10.1084/jem.167.3.954. J Exp Med. 1988. PMID: 3127529 Free PMC article.

8

Studies on the somatic instability of immunoglobulin genes in vivo and in cultured cells.

Scharff MD, Aguila HL, Behar SM, Chien NC, DePinho R, French DL, Pollock RR, Shin SU. Scharff MD, et al. Among authors: chien nc. Immunol Rev. 1987 Apr;96:75-90. doi: 10.1111/j.1600-065x.1987.tb00510.x. Immunol Rev. 1987. PMID: 3298011 Review.

9

The B-cell antigen receptor: structure and function of primary, secondary, tertiary and quaternary components.

Cambier JC, Bedzyk W, Campbell K, Chien N, Friedrich J, Harwood A, Jensen W, Pleiman C, Clark MR. Cambier JC, et al. Among authors: chien n. Immunol Rev. 1993 Apr;132:85-106. doi: 10.1111/j.1600-065x.1993.tb00838.x. Immunol Rev. 1993. PMID: 8349299 Review. No abstract available.

10

Regulation of B cell antigen receptor signal transduction and phosphorylation by CD45.

Justement LB, Campbell KS, Chien NC, Cambier JC. Justement LB, et al. Among authors: chien nc. Science. 1991 Jun 28;252(5014):1839-42. doi: 10.1126/science.1648262. Science. 1991. PMID: 1648262

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