Nicolas JM - Search Results

1

Review of paediatric gastrointestinal physiology relevant to the absorption of orally administered medicines.

Wollmer E, Ungell AL, Nicolas JM, Klein S. Wollmer E, et al. Among authors: nicolas jm. Adv Drug Deliv Rev. 2022 Feb;181:114084. doi: 10.1016/j.addr.2021.114084. Epub 2021 Dec 17. Adv Drug Deliv Rev. 2022. PMID: 34929252 Review.

2

Oral drug absorption in pediatrics: the intestinal wall, its developmental changes and current tools for predictions.

Nicolas JM, Bouzom F, Hugues C, Ungell AL. Nicolas JM, et al. Biopharm Drug Dispos. 2017 Apr;38(3):209-230. doi: 10.1002/bdd.2052. Epub 2017 Feb 6. Biopharm Drug Dispos. 2017. PMID: 27976409 Free PMC article. Review.

3

Use of a physiologically based pharmacokinetic-pharmacodynamic model for initial dose prediction and escalation during a paediatric clinical trial.

Johnson TN, Abduljalil K, Nicolas JM, Muglia P, Chanteux H, Nicolai J, Gillent E, Cornet M, Sciberras D. Johnson TN, et al. Among authors: nicolas jm. Br J Clin Pharmacol. 2021 Mar;87(3):1378-1389. doi: 10.1111/bcp.14528. Epub 2020 Sep 6. Br J Clin Pharmacol. 2021. PMID: 32822519 Free article.

4

Impact of In Vitro Passive Permeability in a P-gp-transfected LLC-PK1 Model on the Prediction of the Rat and Human Unbound Brain-to-Plasma Concentration Ratio.

Nicolaï J, Chapy H, Gillent E, Saunders K, Ungell AL, Nicolas JM, Chanteux H. Nicolaï J, et al. Among authors: nicolas jm. Pharm Res. 2020 Aug 27;37(9):175. doi: 10.1007/s11095-020-02867-z. Pharm Res. 2020. PMID: 32856111

5

Mind the Gaps: Ontogeny of Human Brain P-gp and Its Impact on Drug Toxicity.

Nicolas JM, de Lange ECM. Nicolas JM, et al. AAPS J. 2019 May 28;21(4):67. doi: 10.1208/s12248-019-0340-z. AAPS J. 2019. PMID: 31140038 Review.

6

Confounding parameters in preclinical assessment of blood-brain barrier permeation: an overview with emphasis on species differences and effect of disease states.

Deo AK, Theil FP, Nicolas JM. Deo AK, et al. Among authors: nicolas jm. Mol Pharm. 2013 May 6;10(5):1581-95. doi: 10.1021/mp300570z. Epub 2013 Jan 4. Mol Pharm. 2013. PMID: 23256608 Review.

7

Gender and interindividual variability in pharmacokinetics.

Nicolas JM, Espie P, Molimard M. Nicolas JM, et al. Drug Metab Rev. 2009;41(3):408-21. doi: 10.1080/10837450902891485. Drug Metab Rev. 2009. PMID: 19601720 Review.

8

Role of P-glycoprotein in the brain disposition of seletalisib: Evaluation of the potential for drug-drug interactions.

Nicolas JM, Chanteux H, Nicolaï J, Brouta F, Viot D, Rosseels ML, Gillent E, Bonnaillie P, Mathy FX, Long J, Helmer E. Nicolas JM, et al. Eur J Pharm Sci. 2020 Jan 15;142:105122. doi: 10.1016/j.ejps.2019.105122. Epub 2019 Oct 31. Eur J Pharm Sci. 2020. PMID: 31678424

9

Antiparkinsonian effects of the "Radiprodil and Tozadenant" combination in MPTP-treated marmosets.

Michel A, Nicolas JM, Rose S, Jackson M, Colman P, Briône W, Sciberras D, Muglia P, Scheller DK, Citron M, Downey P. Michel A, et al. Among authors: nicolas jm. PLoS One. 2017 Aug 30;12(8):e0182887. doi: 10.1371/journal.pone.0182887. eCollection 2017. PLoS One. 2017. PMID: 28854243 Free PMC article.

10

Unprecedented therapeutic potential with a combination of A2A/NR2B receptor antagonists as observed in the 6-OHDA lesioned rat model of Parkinson's disease.

Michel A, Downey P, Nicolas JM, Scheller D. Michel A, et al. Among authors: nicolas jm. PLoS One. 2014 Dec 16;9(12):e114086. doi: 10.1371/journal.pone.0114086. eCollection 2014. PLoS One. 2014. PMID: 25513815 Free PMC article.

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