Yamamura N - Search Results

1

CYP2C8-Mediated Formation of a Human Disproportionate Metabolite of the Selective Na_V1.7 Inhibitor DS-1971a, a Mixed Cytochrome P450 and Aldehyde Oxidase Substrate.

Asano D, Hamaue S, Zahir H, Shiozawa H, Nishiya Y, Kimura T, Kazui M, Yamamura N, Ikeguchi M, Shibayama T, Inoue SI, Shinozuka T, Watanabe T, Yahara C, Watanabe N, Yoshinari K. Asano D, et al. Among authors: yamamura n. Drug Metab Dispos. 2022 Mar;50(3):235-242. doi: 10.1124/dmd.121.000665. Epub 2021 Dec 20. Drug Metab Dispos. 2022. PMID: 34930785

2

Panipenum, a carbapenem antibiotic, increases the level of hepatic UDP-glucuronic acid in rats.

Yamamura N, Imura-Miyoshi K, Naganuma H. Yamamura N, et al. Drug Metab Dispos. 2000 Dec;28(12):1484-6. Drug Metab Dispos. 2000. PMID: 11095587

3

Renal handling of CS-023 (RO4908463), a novel parenteral carbapenem antibiotic, in rabbits in comparison with meropenem.

Shibayama T, Yamamura N, Matsushita Y, Tokui T, Hirota T, Ikeda T. Shibayama T, et al. Among authors: yamamura n. Xenobiotica. 2006 Dec;36(12):1273-87. doi: 10.1080/00498250600944326. Xenobiotica. 2006. PMID: 17162472

4

Isolation and identification of diglucuronides of some endogenous steroids in dogs.

Murai T, Yamamura N, Nitanai T, Samata N, Takei M, Iwabuchi H, Tanaka K, Mikamoto K, Ikeda T. Murai T, et al. Among authors: yamamura n. Drug Metab Dispos. 2008 Feb;36(2):368-74. doi: 10.1124/dmd.107.019059. Epub 2007 Nov 15. Drug Metab Dispos. 2008. PMID: 18006648

5

Identification of novel metabolic pathways of pioglitazone in hepatocytes: N-glucuronidation of thiazolidinedione ring and sequential ring-opening pathway.

Uchiyama M, Fischer T, Mueller J, Oguchi M, Yamamura N, Koda H, Iwabuchi H, Izumi T. Uchiyama M, et al. Among authors: yamamura n. Drug Metab Dispos. 2010 Jun;38(6):946-56. doi: 10.1124/dmd.109.031583. Epub 2010 Feb 25. Drug Metab Dispos. 2010. PMID: 20185540

6

Identification of valproic acid glucuronide hydrolase as a key enzyme for the interaction of valproic acid with carbapenem antibiotics.

Suzuki E, Yamamura N, Ogura Y, Nakai D, Kubota K, Kobayashi N, Miura S, Okazaki O. Suzuki E, et al. Among authors: yamamura n. Drug Metab Dispos. 2010 Sep;38(9):1538-44. doi: 10.1124/dmd.110.032938. Epub 2010 Jun 15. Drug Metab Dispos. 2010. PMID: 20551238

7

In vitro metabolism of rivoglitazone, a novel peroxisome proliferator-activated receptor γ agonist, in rat, monkey, and human liver microsomes and freshly isolated hepatocytes.

Uchiyama M, Koda H, Fischer T, Mueller J, Yamamura N, Oguchi M, Iwabuchi H, Okazaki O, Izumi T. Uchiyama M, et al. Among authors: yamamura n. Drug Metab Dispos. 2011 Jul;39(7):1311-9. doi: 10.1124/dmd.111.038729. Epub 2011 Apr 21. Drug Metab Dispos. 2011. PMID: 21511943

8

Coadministration of probenecid and cimetidine with mirogabalin in healthy subjects: A phase 1, randomized, open-label, drug-drug interaction study.

Tachibana M, Yamamura N, Atiee GJ, Hsu C, Warren V, He L, Dishy V, Zahir H. Tachibana M, et al. Among authors: yamamura n. Br J Clin Pharmacol. 2018 Oct;84(10):2317-2324. doi: 10.1111/bcp.13674. Epub 2018 Aug 9. Br J Clin Pharmacol. 2018. PMID: 29920736 Free PMC article. Clinical Trial.

9

Pharmacokinetics and metabolism of mirogabalin, a novel α₂δ ligand, in rats and monkeys.

Yamamura N, Uchiyama M, Takahashi M, Honda T, Nishiya Y. Yamamura N, et al. Xenobiotica. 2022 Jan;52(1):54-64. doi: 10.1080/00498254.2022.2049396. Epub 2022 Mar 10. Xenobiotica. 2022. PMID: 35249464

10

Tissue distribution of renadirsen sodium, a dystrophin exon-skipping antisense oligonucleotide, in heart and diaphragm after subcutaneous administration to cynomolgus monkeys.

Yamamura N, Takakusa H, Asano D, Watanabe K, Shibaya Y, Yamanaka R, Fusegawa K, Kanda A, Nagase H, Takaishi K, Koizumi M, Takeshima Y, Matsuo M. Yamamura N, et al. Nucleosides Nucleotides Nucleic Acids. 2024 Aug 10:1-17. doi: 10.1080/15257770.2024.2389545. Online ahead of print. Nucleosides Nucleotides Nucleic Acids. 2024. PMID: 39126396

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