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CYP2C8-Mediated Formation of a Human Disproportionate Metabolite of the Selective NaV1.7 Inhibitor DS-1971a, a Mixed Cytochrome P450 and Aldehyde Oxidase Substrate.
Asano D, Hamaue S, Zahir H, Shiozawa H, Nishiya Y, Kimura T, Kazui M, Yamamura N, Ikeguchi M, Shibayama T, Inoue SI, Shinozuka T, Watanabe T, Yahara C, Watanabe N, Yoshinari K. Asano D, et al. Among authors: yoshinari k. Drug Metab Dispos. 2022 Mar;50(3):235-242. doi: 10.1124/dmd.121.000665. Epub 2021 Dec 20. Drug Metab Dispos. 2022. PMID: 34930785
Dietary inulin alleviates hepatic steatosis and xenobiotics-induced liver injury in rats fed a high-fat and high-sucrose diet: association with the suppression of hepatic cytochrome P450 and hepatocyte nuclear factor 4alpha expression.
Sugatani J, Wada T, Osabe M, Yamakawa K, Yoshinari K, Miwa M. Sugatani J, et al. Among authors: yoshinari k. Drug Metab Dispos. 2006 Oct;34(10):1677-87. doi: 10.1124/dmd.106.010645. Epub 2006 Jun 30. Drug Metab Dispos. 2006. PMID: 16815962
196 results