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Page 1
Insulin signalling in tanycytes gates hypothalamic insulin uptake and regulation of AgRP neuron activity.
Porniece Kumar M, Cremer AL, Klemm P, Steuernagel L, Sundaram S, Jais A, Hausen AC, Tao J, Secher A, Pedersen TÅ, Schwaninger M, Wunderlich FT, Lowell BB, Backes H, Brüning JC. Porniece Kumar M, et al. Among authors: backes h. Nat Metab. 2021 Dec;3(12):1662-1679. doi: 10.1038/s42255-021-00499-0. Epub 2021 Dec 20. Nat Metab. 2021. PMID: 34931084 Free PMC article.
AgRP Neurons Control Systemic Insulin Sensitivity via Myostatin Expression in Brown Adipose Tissue.
Steculorum SM, Ruud J, Karakasilioti I, Backes H, Engström Ruud L, Timper K, Hess ME, Tsaousidou E, Mauer J, Vogt MC, Paeger L, Bremser S, Klein AC, Morgan DA, Frommolt P, Brinkkötter PT, Hammerschmidt P, Benzing T, Rahmouni K, Wunderlich FT, Kloppenburg P, Brüning JC. Steculorum SM, et al. Among authors: backes h. Cell. 2016 Mar 24;165(1):125-138. doi: 10.1016/j.cell.2016.02.044. Cell. 2016. PMID: 27015310 Free PMC article.
Myeloid-Cell-Derived VEGF Maintains Brain Glucose Uptake and Limits Cognitive Impairment in Obesity.
Jais A, Solas M, Backes H, Chaurasia B, Kleinridders A, Theurich S, Mauer J, Steculorum SM, Hampel B, Goldau J, Alber J, Förster CY, Eming SA, Schwaninger M, Ferrara N, Karsenty G, Brüning JC. Jais A, et al. Among authors: backes h. Cell. 2016 May 5;165(4):882-95. doi: 10.1016/j.cell.2016.03.033. Epub 2016 Apr 28. Cell. 2016. PMID: 27133169 Free article.
Myeloid-Cell-Derived VEGF Maintains Brain Glucose Uptake and Limits Cognitive Impairment in Obesity.
Jais A, Solas M, Backes H, Chaurasia B, Kleinridders A, Theurich S, Mauer J, Steculorum SM, Hampel B, Goldau J, Alber J, Förster CY, Eming SA, Schwaninger M, Ferrara N, Karsenty G, Brüning JC. Jais A, et al. Among authors: backes h. Cell. 2016 Aug 25;166(5):1338-1340. doi: 10.1016/j.cell.2016.08.010. Cell. 2016. PMID: 27565353 Free article. No abstract available.
Time-dependent assessment of stimulus-evoked regional dopamine release.
Lippert RN, Cremer AL, Edwin Thanarajah S, Korn C, Jahans-Price T, Burgeno LM, Tittgemeyer M, Brüning JC, Walton ME, Backes H. Lippert RN, et al. Among authors: backes h. Nat Commun. 2019 Jan 18;10(1):336. doi: 10.1038/s41467-018-08143-4. Nat Commun. 2019. PMID: 30659189 Free PMC article.
Thyroid-Hormone-Induced Browning of White Adipose Tissue Does Not Contribute to Thermogenesis and Glucose Consumption.
Johann K, Cremer AL, Fischer AW, Heine M, Pensado ER, Resch J, Nock S, Virtue S, Harder L, Oelkrug R, Astiz M, Brabant G, Warner A, Vidal-Puig A, Oster H, Boelen A, López M, Heeren J, Dalley JW, Backes H, Mittag J. Johann K, et al. Among authors: backes h. Cell Rep. 2019 Jun 11;27(11):3385-3400.e3. doi: 10.1016/j.celrep.2019.05.054. Cell Rep. 2019. PMID: 31189119 Free article.
PNOCARC Neurons Promote Hyperphagia and Obesity upon High-Fat-Diet Feeding.
Jais A, Paeger L, Sotelo-Hitschfeld T, Bremser S, Prinzensteiner M, Klemm P, Mykytiuk V, Widdershooven PJM, Vesting AJ, Grzelka K, Minère M, Cremer AL, Xu J, Korotkova T, Lowell BB, Zeilhofer HU, Backes H, Fenselau H, Wunderlich FT, Kloppenburg P, Brüning JC. Jais A, et al. Among authors: backes h. Neuron. 2020 Jun 17;106(6):1009-1025.e10. doi: 10.1016/j.neuron.2020.03.022. Epub 2020 Apr 16. Neuron. 2020. PMID: 32302532 Free PMC article.
GLP-1 Receptor Signaling in Astrocytes Regulates Fatty Acid Oxidation, Mitochondrial Integrity, and Function.
Timper K, Del Río-Martín A, Cremer AL, Bremser S, Alber J, Giavalisco P, Varela L, Heilinger C, Nolte H, Trifunovic A, Horvath TL, Kloppenburg P, Backes H, Brüning JC. Timper K, et al. Among authors: backes h. Cell Metab. 2020 Jun 2;31(6):1189-1205.e13. doi: 10.1016/j.cmet.2020.05.001. Epub 2020 May 19. Cell Metab. 2020. PMID: 32433922 Free PMC article.
67 results