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Toward a Practical, Nonenzymatic Process for Investigational COVID-19 Antiviral Molnupiravir from Cytidine: Supply-Centered Synthesis.
Gopalsamuthiram V, Kadam AL, Noble JK, Snead DR, Williams C, Jamison TF, Senanayake C, Yadaw AK, Roy S, Sirasani G, Gupton BF, Burns J, Cook DW, Stringham RW, Ahmad S, Krack R. Gopalsamuthiram V, et al. Among authors: kadam al. Org Process Res Dev. 2021 Dec 17;25(12):2679-2685. doi: 10.1021/acs.oprd.1c00219. Epub 2021 Dec 9. Org Process Res Dev. 2021. PMID: 34955627 Free PMC article. Review.
Practical and Scalable Two-Step Process for 6-(2-Fluoro-4-nitrophenyl)-2-oxa-6-azaspiro[3.3]heptane: A Key Intermediate of the Potent Antibiotic Drug Candidate TBI-223.
Cardoso FSP, Kadam AL, Nelson RC, Tomlin JW, Dahal D, Kuehner CS, Gudvangen G, Arduengo AJ 3rd, Burns JM, Aleshire SL, Snead DR, Qu F, Belmore K, Ahmad S, Agrawal T, Sieber JD, Donsbach KO. Cardoso FSP, et al. Among authors: kadam al. Org Process Res Dev. 2023 Jul 12;27(7):1390-1399. doi: 10.1021/acs.oprd.3c00148. eCollection 2023 Jul 21. Org Process Res Dev. 2023. PMID: 37496954 Free PMC article.
20 results