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A selective CuII complex with 4-fluorophenoxyacetic acid hydrazide and phenanthroline displays DNA-cleaving and pro-apoptotic properties in cancer cells.
Machado PHA, Paixão DA, Lino RC, de Souza TR, de Souza Bontempo NJ, Sousa LM, Van Petten de Vasconcelos Azevedo F, Orsolin PC, Lima PMAP, Martins IC, da Costa Guerra JF, Teixeira SC, Araújo TG, Goulart LR, Morelli S, Guerra W, de Oliveira Júnior RJ. Machado PHA, et al. Sci Rep. 2021 Dec 27;11(1):24450. doi: 10.1038/s41598-021-03909-1. Sci Rep. 2021. PMID: 34961767 Free PMC article.
Using native and invasive livebearing fishes (Poeciliidae, Teleostei) for the integrated biological assessment of pollution in urban streams.
Gomes-Silva G, Pereira BB, Liu K, Chen B, Santos VSV, de Menezes GHT, Pires LP, Santos BMT, Oliveira DM, Machado PHA, de Oliveira Júnior RJ, de Oliveira AMM, Plath M. Gomes-Silva G, et al. Among authors: machado pha. Sci Total Environ. 2020 Jan 1;698:134336. doi: 10.1016/j.scitotenv.2019.134336. Epub 2019 Sep 6. Sci Total Environ. 2020. PMID: 31783440
Copper(II) Complex Containing 4-Fluorophenoxyacetic Acid Hydrazide and 1,10-Phenanthroline: A Prostate Cancer Cell-Selective and Low-Toxic Copper(II) Compound.
Bontempo NJS, Paixão DA, Lima PMAP, Barros DCT, Borges DS, Orsolin PC, Martins IC, Machado PHA, Lino RC, Souza TR, Ramos LMS, Teixeira SC, Siqueira RP, Goulart Filho LR, Guerra W, Oliveira Júnior RJ, Araújo TG. Bontempo NJS, et al. Among authors: machado pha. Molecules. 2022 Oct 20;27(20):7097. doi: 10.3390/molecules27207097. Molecules. 2022. PMID: 36296690 Free PMC article.