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Page 1
Measurements of 5,6-Orthoquinone, a Surrogate for the Presumed Active Primaquine Metabolite 5-Hydroxyprimaquine, in the Urine of Cambodian Adults.
Vanachayangkul P, Sea D, Wojnarski M, Sok S, Kodchakorn C, Ta-Aksorn W, Hom S, Ittiverakul M, Kuntawunginn W, Arsanok M, Buathong N, Heng TK, Nareth K, Nou S, Chandara S, Ly S, Oung P, Vesely B, Bennett J, Reichard G, Pybus B, Lanteri C, Saunders D, Fukuda M, Smith P, Dysoley L, Rekol H, Waters NC, Spring M. Vanachayangkul P, et al. Among authors: smith p. Antimicrob Agents Chemother. 2022 Mar 15;66(3):e0182121. doi: 10.1128/AAC.01821-21. Epub 2022 Jan 3. Antimicrob Agents Chemother. 2022. PMID: 34978892 Free PMC article.
Utility of alkylaminoquinolinyl methanols as new antimalarial drugs.
Dow GS, Heady TN, Bhattacharjee AK, Caridha D, Gerena L, Gettayacamin M, Lanteri CA, Obaldia N 3rd, Roncal N, Shearer T, Smith PL, Tungtaeng A, Wolf L, Cabezas M, Yourick D, Smith KS. Dow GS, et al. Among authors: smith pl, smith ks. Antimicrob Agents Chemother. 2006 Dec;50(12):4132-43. doi: 10.1128/AAC.00631-06. Epub 2006 Sep 11. Antimicrob Agents Chemother. 2006. PMID: 16966402 Free PMC article.
Differential CYP 2D6 metabolism alters primaquine pharmacokinetics.
Potter BM, Xie LH, Vuong C, Zhang J, Zhang P, Duan D, Luong TL, Bandara Herath HM, Dhammika Nanayakkara NP, Tekwani BL, Walker LA, Nolan CK, Sciotti RJ, Zottig VE, Smith PL, Paris RM, Read LT, Li Q, Pybus BS, Sousa JC, Reichard GA, Marcsisin SR. Potter BM, et al. Among authors: smith pl. Antimicrob Agents Chemother. 2015 Apr;59(4):2380-7. doi: 10.1128/AAC.00015-15. Epub 2015 Feb 2. Antimicrob Agents Chemother. 2015. PMID: 25645856 Free PMC article.
Differential cytochrome P450 2D metabolism alters tafenoquine pharmacokinetics.
Vuong C, Xie LH, Potter BM, Zhang J, Zhang P, Duan D, Nolan CK, Sciotti RJ, Zottig VE, Nanayakkara NP, Tekwani BL, Walker LA, Smith PL, Paris RM, Read LT, Li Q, Pybus BS, Sousa JC, Reichard GA, Smith B, Marcsisin SR. Vuong C, et al. Among authors: smith pl, smith b. Antimicrob Agents Chemother. 2015 Jul;59(7):3864-9. doi: 10.1128/AAC.00343-15. Epub 2015 Apr 13. Antimicrob Agents Chemother. 2015. PMID: 25870069 Free PMC article.
Ex vivo piperaquine resistance developed rapidly in Plasmodium falciparum isolates in northern Cambodia compared to Thailand.
Chaorattanakawee S, Lon C, Jongsakul K, Gawee J, Sok S, Sundrakes S, Kong N, Thamnurak C, Chann S, Chattrakarn S, Praditpol C, Buathong N, Uthaimongkol N, Smith P, Sirisopana N, Huy R, Prom S, Fukuda MM, Bethell D, Walsh DS, Lanteri C, Saunders D. Chaorattanakawee S, et al. Among authors: smith p. Malar J. 2016 Oct 21;15(1):519. doi: 10.1186/s12936-016-1569-y. Malar J. 2016. PMID: 27769299 Free PMC article. Clinical Trial.
Chemoprophylaxis with sporozoite immunization in P. knowlesi rhesus monkeys confers protection and elicits sporozoite-specific memory T cells in the liver.
Pichyangkul S, Spring MD, Yongvanitchit K, Kum-Arb U, Limsalakpetch A, Im-Erbsin R, Ubalee R, Vanachayangkul P, Remarque EJ, Angov E, Smith PL, Saunders DL. Pichyangkul S, et al. Among authors: smith pl. PLoS One. 2017 Feb 9;12(2):e0171826. doi: 10.1371/journal.pone.0171826. eCollection 2017. PLoS One. 2017. PMID: 28182750 Free PMC article.
Gametocyte Carriage, Antimalarial Use, and Drug Resistance in Cambodia, 2008-2014.
Lin JT, Patel JC, Levitz L, Wojnarski M, Chaorattanakawee S, Gosi P, Buathong N, Chann S, Huy R, Thay K, Sea D, Samon N, Takala-Harrison S, Fukuda M, Smith P, Spring M, Saunders D, Lon C. Lin JT, et al. Among authors: smith p. Am J Trop Med Hyg. 2018 Nov;99(5):1145-1149. doi: 10.4269/ajtmh.18-0509. Am J Trop Med Hyg. 2018. PMID: 30226145 Free PMC article.
Cluster-randomized trial of monthly malaria prophylaxis versus focused screening and treatment: a study protocol to define malaria elimination strategies in Cambodia.
Manning J, Lon C, Spring M, Wojnarski M, Somethy S, Chann S, Gosi P, Soveasna K, Sriwichai S, Kuntawunginn W, Fukuda MM, Smith PL, Rekol H, Sinoun M, So M, Lin J, Satharath P, Saunders D. Manning J, et al. Among authors: smith pl. Trials. 2018 Oct 16;19(1):558. doi: 10.1186/s13063-018-2931-x. Trials. 2018. PMID: 30326952 Free PMC article.
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