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214 results

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Human KIR + CD8 + T cells target pathogenic T cells in Celiac disease and are active in autoimmune diseases and COVID-19.
Li J, Zaslavsky M, Su Y, Sikora MJ, van Unen V, Christophersen A, Chiou SH, Chen L, Li J, Ji X, Wilhelmy J, McSween AM, Palanski BA, Aditya Mallajosyula VV, Dhondalay GKR, Bhamidipati K, Pai J, Kipp LB, Dunn JE, Hauser SL, Oksenberg JR, Satpathy AT, Robinson WH, Steinmetz LM, Khosla C, Utz PJ, Sollid LM, Heath JR, Fernandez-Becker NQ, Nadeau KC, Saligrama N, Davis MM. Li J, et al. Among authors: steinmetz lm. bioRxiv [Preprint]. 2021 Dec 25:2021.12.23.473930. doi: 10.1101/2021.12.23.473930. bioRxiv. 2021. Update in: Science. 2022 Apr 15;376(6590):eabi9591. doi: 10.1126/science.abi9591 PMID: 34981055 Free PMC article. Updated. Preprint.
Opposing T cell responses in experimental autoimmune encephalomyelitis.
Saligrama N, Zhao F, Sikora MJ, Serratelli WS, Fernandes RA, Louis DM, Yao W, Ji X, Idoyaga J, Mahajan VB, Steinmetz LM, Chien YH, Hauser SL, Oksenberg JR, Garcia KC, Davis MM. Saligrama N, et al. Among authors: steinmetz lm. Nature. 2019 Aug;572(7770):481-487. doi: 10.1038/s41586-019-1467-x. Epub 2019 Aug 7. Nature. 2019. PMID: 31391585 Free PMC article.
KIR+CD8+ T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19.
Li J, Zaslavsky M, Su Y, Guo J, Sikora MJ, van Unen V, Christophersen A, Chiou SH, Chen L, Li J, Ji X, Wilhelmy J, McSween AM, Palanski BA, Mallajosyula VVA, Bracey NA, Dhondalay GKR, Bhamidipati K, Pai J, Kipp LB, Dunn JE, Hauser SL, Oksenberg JR, Satpathy AT, Robinson WH, Dekker CL, Steinmetz LM, Khosla C, Utz PJ, Sollid LM, Chien YH, Heath JR, Fernandez-Becker NQ, Nadeau KC, Saligrama N, Davis MM. Li J, et al. Among authors: steinmetz lm. Science. 2022 Apr 15;376(6590):eabi9591. doi: 10.1126/science.abi9591. Epub 2022 Apr 15. Science. 2022. PMID: 35258337 Free PMC article.
An encyclopedia of enhancer-gene regulatory interactions in the human genome.
Gschwind AR, Mualim KS, Karbalayghareh A, Sheth MU, Dey KK, Jagoda E, Nurtdinov RN, Xi W, Tan AS, Jones H, Ma XR, Yao D, Nasser J, Avsec Ž, James BT, Shamim MS, Durand NC, Rao SSP, Mahajan R, Doughty BR, Andreeva K, Ulirsch JC, Fan K, Perez EM, Nguyen TC, Kelley DR, Finucane HK, Moore JE, Weng Z, Kellis M, Bassik MC, Price AL, Beer MA, Guigó R, Stamatoyannopoulos JA, Lieberman Aiden E, Greenleaf WJ, Leslie CS, Steinmetz LM, Kundaje A, Engreitz JM. Gschwind AR, et al. Among authors: steinmetz lm. bioRxiv [Preprint]. 2023 Nov 13:2023.11.09.563812. doi: 10.1101/2023.11.09.563812. bioRxiv. 2023. PMID: 38014075 Free PMC article. Preprint.
Dissecting quantitative trait nucleotides by saturation genome editing.
Roy KR, Smith JD, Li S, Vonesch SC, Nguyen M, Burnett WT, Orsley KM, Lee CS, Haber JE, St Onge RP, Steinmetz LM. Roy KR, et al. Among authors: steinmetz lm. bioRxiv [Preprint]. 2024 Feb 2:2024.02.02.577784. doi: 10.1101/2024.02.02.577784. bioRxiv. 2024. PMID: 38352467 Free PMC article. Preprint.
Genome-scale analysis of interactions between genetic perturbations and natural variation.
Hale JJ, Matsui T, Goldstein I, Mullis MN, Roy KR, Ville CN, Miller D, Wang C, Reynolds T, Steinmetz LM, Levy SF, Ehrenreich IM. Hale JJ, et al. Among authors: steinmetz lm. bioRxiv [Preprint]. 2024 Jan 16:2023.05.06.539663. doi: 10.1101/2023.05.06.539663. bioRxiv. 2024. Update in: Nat Commun. 2024 May 18;15(1):4234. doi: 10.1038/s41467-024-48626-1 PMID: 38293072 Free PMC article. Updated. Preprint.
Genome sequencing and comparative analysis of Saccharomyces cerevisiae strain YJM789.
Wei W, McCusker JH, Hyman RW, Jones T, Ning Y, Cao Z, Gu Z, Bruno D, Miranda M, Nguyen M, Wilhelmy J, Komp C, Tamse R, Wang X, Jia P, Luedi P, Oefner PJ, David L, Dietrich FS, Li Y, Davis RW, Steinmetz LM. Wei W, et al. Among authors: steinmetz lm. Proc Natl Acad Sci U S A. 2007 Jul 31;104(31):12825-30. doi: 10.1073/pnas.0701291104. Epub 2007 Jul 25. Proc Natl Acad Sci U S A. 2007. PMID: 17652520 Free PMC article.
214 results