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Mammalian Systems Biotechnology Reveals Global Cellular Adaptations in a Recombinant CHO Cell Line.
Yusufi FNK, Lakshmanan M, Ho YS, Loo BLW, Ariyaratne P, Yang Y, Ng SK, Tan TRM, Yeo HC, Lim HL, Ng SW, Hiu AP, Chow CP, Wan C, Chen S, Teo G, Song G, Chin JX, Ruan X, Sung KWK, Hu WS, Yap MGS, Bardor M, Nagarajan N, Lee DY. Yusufi FNK, et al. Among authors: lakshmanan m. Cell Syst. 2017 May 24;4(5):530-542.e6. doi: 10.1016/j.cels.2017.04.009. Cell Syst. 2017. PMID: 28544881 Free article.
Multi-omics profiling of a CHO cell culture system unravels the effect of culture pH on cell growth, antibody titer, and product quality.
Lee AP, Kok YJ, Lakshmanan M, Leong D, Zheng L, Lim HL, Chen S, Mak SY, Ang KS, Templeton N, Salim T, Wei X, Gifford E, Tan AH, Bi X, Ng SK, Lee DY, Ling WLW, Ho YS. Lee AP, et al. Among authors: lakshmanan m. Biotechnol Bioeng. 2021 Nov;118(11):4305-4316. doi: 10.1002/bit.27899. Epub 2021 Jul 31. Biotechnol Bioeng. 2021. PMID: 34289087
Enzyme capacity-based genome scale modelling of CHO cells.
Yeo HC, Hong J, Lakshmanan M, Lee DY. Yeo HC, et al. Among authors: lakshmanan m. Metab Eng. 2020 Jul;60:138-147. doi: 10.1016/j.ymben.2020.04.005. Epub 2020 Apr 21. Metab Eng. 2020. PMID: 32330653
Enhancing Microbiome Research through Genome-Scale Metabolic Modeling.
Ankrah NYD, Bernstein DB, Biggs M, Carey M, Engevik M, García-Jiménez B, Lakshmanan M, Pacheco AR, Sulheim S, Medlock GL. Ankrah NYD, et al. Among authors: lakshmanan m. mSystems. 2021 Dec 21;6(6):e0059921. doi: 10.1128/mSystems.00599-21. Epub 2021 Dec 14. mSystems. 2021. PMID: 34904863 Free PMC article.
321 results