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Page 1
Role of Tyrosine Kinase Syk in Thrombus Stabilisation at High Shear.
Perrella G, Montague SJ, Brown HC, Garcia Quintanilla L, Slater A, Stegner D, Thomas M, Heemskerk JWM, Watson SP. Perrella G, et al. Among authors: montague sj. Int J Mol Sci. 2022 Jan 1;23(1):493. doi: 10.3390/ijms23010493. Int J Mol Sci. 2022. PMID: 35008919 Free PMC article.
Activation of glycoprotein VI (GPVI) and C-type lectin-like receptor-2 (CLEC-2) underlies platelet activation by diesel exhaust particles and other charged/hydrophobic ligands.
Alshehri OM, Montague S, Watson S, Carter P, Sarker N, Manne BK, Miller JL, Herr AB, Pollitt AY, O'Callaghan CA, Kunapuli S, Arman M, Hughes CE, Watson SP. Alshehri OM, et al. Biochem J. 2015 Jun 15;468(3):459-73. doi: 10.1042/BJ20150192. Epub 2015 Apr 7. Biochem J. 2015. PMID: 25849538
Fibrin activates GPVI in human and mouse platelets.
Alshehri OM, Hughes CE, Montague S, Watson SK, Frampton J, Bender M, Watson SP. Alshehri OM, et al. Blood. 2015 Sep 24;126(13):1601-8. doi: 10.1182/blood-2015-04-641654. Epub 2015 Aug 17. Blood. 2015. PMID: 26282541 Free PMC article.
Soluble GPVI is elevated in injured patients: shedding is mediated by fibrin activation of GPVI.
Montague SJ, Delierneux C, Lecut C, Layios N, Dinsdale RJ, Lee CS, Poulter NS, Andrews RK, Hampson P, Wearn CM, Maes N, Bishop J, Bamford A, Gardiner C, Lee WM, Iqbal T, Moiemen N, Watson SP, Oury C, Harrison P, Gardiner EE. Montague SJ, et al. Blood Adv. 2018 Feb 13;2(3):240-251. doi: 10.1182/bloodadvances.2017011171. Blood Adv. 2018. PMID: 29437639 Free PMC article.
Inhibition of Btk by Btk-specific concentrations of ibrutinib and acalabrutinib delays but does not block platelet aggregation mediated by glycoprotein VI.
Nicolson PLR, Hughes CE, Watson S, Nock SH, Hardy AT, Watson CN, Montague SJ, Clifford H, Huissoon AP, Malcor JD, Thomas MR, Pollitt AY, Tomlinson MG, Pratt G, Watson SP. Nicolson PLR, et al. Among authors: montague sj. Haematologica. 2018 Dec;103(12):2097-2108. doi: 10.3324/haematol.2018.193391. Epub 2018 Jul 19. Haematologica. 2018. PMID: 30026342 Free PMC article.
Antiplatelet drugs block platelet activation by VITT patient serum.
Smith CW, Montague SJ, Kardeby C, Di Y, Lowe GC, Lester WA, Watson SP, Nicolson PLR. Smith CW, et al. Among authors: montague sj. Blood. 2021 Dec 23;138(25):2733-2740. doi: 10.1182/blood.2021012277. Blood. 2021. PMID: 34375398 Free PMC article. No abstract available.
39 results