Ibrahim MK - Search Results

1

Design, synthesis, in silico ADMET, docking, and antiproliferative evaluations of [1,2,4]triazolo[4,3-c]quinazolines as classical DNA intercalators.

Alesawy MS, Ibrahim MK, Eissa IH, El-Adl K. Alesawy MS, et al. Among authors: ibrahim mk. Arch Pharm (Weinheim). 2022 Apr;355(4):e2100412. doi: 10.1002/ardp.202100412. Epub 2022 Jan 10. Arch Pharm (Weinheim). 2022. PMID: 35014084

2

Design, synthesis, molecular modeling and anti-proliferative evaluation of novel quinoxaline derivatives as potential DNA intercalators and topoisomerase II inhibitors.

Ibrahim MK, Taghour MS, Metwaly AM, Belal A, Mehany ABM, Elhendawy MA, Radwan MM, Yassin AM, El-Deeb NM, Hafez EE, ElSohly MA, Eissa IH. Ibrahim MK, et al. Eur J Med Chem. 2018 Jul 15;155:117-134. doi: 10.1016/j.ejmech.2018.06.004. Epub 2018 Jun 4. Eur J Med Chem. 2018. PMID: 29885574

3

N-Substituted-4-phenylphthalazin-1-amine-derived VEGFR-2 inhibitors: Design, synthesis, molecular docking, and anticancer evaluation studies.

El-Adl K, Ibrahim MK, Khedr F, Abulkhair HS, Eissa IH. El-Adl K, et al. Among authors: ibrahim mk. Arch Pharm (Weinheim). 2021 Mar;354(3):e2000219. doi: 10.1002/ardp.202000219. Epub 2020 Nov 16. Arch Pharm (Weinheim). 2021. PMID: 33197080

4

[1,2,4]Triazolo[4,3-c]quinazoline and bis([1,2,4]triazolo)[4,3-a:4',3'-c]quinazoline derived DNA intercalators: Design, synthesis, in silico ADMET profile, molecular docking and anti-proliferative evaluation studies.

El-Adl K, Ibrahim MK, Alesawy MSI, Eissa IH. El-Adl K, et al. Among authors: ibrahim mk. Bioorg Med Chem. 2021 Jan 15;30:115958. doi: 10.1016/j.bmc.2020.115958. Epub 2020 Dec 21. Bioorg Med Chem. 2021. PMID: 33360576

5

Phthalazine-based VEGFR-2 inhibitors: Rationale, design, synthesis, in silico, ADMET profile, docking, and anticancer evaluations.

Khedr F, Ibrahim MK, Eissa IH, Abulkhair HS, El-Adl K. Khedr F, et al. Among authors: ibrahim mk. Arch Pharm (Weinheim). 2021 Nov;354(11):e2100201. doi: 10.1002/ardp.202100201. Epub 2021 Aug 19. Arch Pharm (Weinheim). 2021. PMID: 34411344

6

Antiproliferative evaluations of triazoloquinazolines as classical DNA intercalators: Design, synthesis, ADMET profile, and molecular docking.

Eissa IH, Ibrahim MK, Alesawy MS, El-Adl K. Eissa IH, et al. Among authors: ibrahim mk. Arch Pharm (Weinheim). 2022 May;355(5):e2100487. doi: 10.1002/ardp.202100487. Epub 2022 Feb 23. Arch Pharm (Weinheim). 2022. PMID: 35194810

7

Triazoloquinazoline derived classical DNA intercalators: Design, synthesis, in silico ADME profile, docking, and antiproliferative evaluations.

El-Adl K, Ibrahim MK, Alesawy MS, Eissa IH. El-Adl K, et al. Among authors: ibrahim mk. Arch Pharm (Weinheim). 2022 Jun;355(6):e2100506. doi: 10.1002/ardp.202100506. Epub 2022 Mar 16. Arch Pharm (Weinheim). 2022. PMID: 35293628

8

Exploration of the VEGFR-2 inhibition activity of phthalazine derivatives: design, synthesis, cytotoxicity, ADMET, molecular docking and dynamic simulation.

Bayoumi HH, Ibrahim MK, Dahab MA, Khedr F, El-Adl K. Bayoumi HH, et al. Among authors: ibrahim mk. RSC Adv. 2024 Jul 8;14(30):21668-21681. doi: 10.1039/d4ra03459g. eCollection 2024 Jul 5. RSC Adv. 2024. PMID: 38979468 Free PMC article.

9

Rationale, in silico docking, ADMET profile, design, synthesis and cytotoxicity evaluations of phthalazine derivatives as VEGFR-2 inhibitors and apoptosis inducers.

Bayoumi HH, Ibrahim MK, Dahab MA, Khedr F, El-Adl K. Bayoumi HH, et al. Among authors: ibrahim mk. RSC Adv. 2024 Aug 27;14(37):27110-27121. doi: 10.1039/d4ra04956j. eCollection 2024 Aug 22. RSC Adv. 2024. PMID: 39193307 Free PMC article.

10

Phthalazine Derivatives as VEGFR-2 Inhibitors: Docking, ADMET, Synthesis, Design, Anticancer Evaluations, and Apoptosis Inducers.

Bayoumi HH, Ibrahim MK, Dahab MA, Khedr F, El-Adl K. Bayoumi HH, et al. Among authors: ibrahim mk. Drug Dev Res. 2025 Feb;86(1):e70037. doi: 10.1002/ddr.70037. Drug Dev Res. 2025. PMID: 39717939

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