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Page 1
Stable flow-induced expression of KLK10 inhibits endothelial inflammation and atherosclerosis.
Williams D, Mahmoud M, Liu R, Andueza A, Kumar S, Kang DW, Zhang J, Tamargo I, Villa-Roel N, Baek KI, Lee H, An Y, Zhang L, Tate EW, Bagchi P, Pohl J, Mosnier LO, Diamandis EP, Mihara K, Hollenberg MD, Dai Z, Jo H. Williams D, et al. Among authors: villa roel n. Elife. 2022 Jan 11;11:e72579. doi: 10.7554/eLife.72579. Elife. 2022. PMID: 35014606 Free PMC article.
Disturbed Flow Increases UBE2C (Ubiquitin E2 Ligase C) via Loss of miR-483-3p, Inducing Aortic Valve Calcification by the pVHL (von Hippel-Lindau Protein) and HIF-1α (Hypoxia-Inducible Factor-1α) Pathway in Endothelial Cells.
Fernandez Esmerats J, Villa-Roel N, Kumar S, Gu L, Salim MT, Ohh M, Taylor WR, Nerem RM, Yoganathan AP, Jo H. Fernandez Esmerats J, et al. Among authors: villa roel n. Arterioscler Thromb Vasc Biol. 2019 Mar;39(3):467-481. doi: 10.1161/ATVBAHA.118.312233. Arterioscler Thromb Vasc Biol. 2019. PMID: 30602302 Free PMC article.
HEG1 Protects Against Atherosclerosis by Regulating Stable Flow-Induced KLF2/4 Expression in Endothelial Cells.
Tamargo IA, Baek KI, Xu C, Kang DW, Kim Y, Andueza A, Williams D, Demos C, Villa-Roel N, Kumar S, Park C, Choi R, Johnson J, Chang S, Kim P, Tan S, Jeong K, Tsuji S, Jo H. Tamargo IA, et al. Among authors: villa roel n. Circulation. 2024 Apr 9;149(15):1183-1201. doi: 10.1161/CIRCULATIONAHA.123.064735. Epub 2023 Dec 15. Circulation. 2024. PMID: 38099436
Myeloid CCN3 protects against aortic valve calcification.
Tu P, Xu Q, Zhou X, Villa-Roel N, Kumar S, Dong N, Jo H, Ou C, Lin Z. Tu P, et al. Among authors: villa roel n. Cell Commun Signal. 2023 Jan 20;21(1):14. doi: 10.1186/s12964-022-01020-0. Cell Commun Signal. 2023. PMID: 36670446 Free PMC article.