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Page 1
Magnesium sensing via LFA-1 regulates CD8+ T cell effector function.
Lötscher J, Martí I Líndez AA, Kirchhammer N, Cribioli E, Giordano Attianese GMP, Trefny MP, Lenz M, Rothschild SI, Strati P, Künzli M, Lotter C, Schenk SH, Dehio P, Löliger J, Litzler L, Schreiner D, Koch V, Page N, Lee D, Grählert J, Kuzmin D, Burgener AV, Merkler D, Pless M, Balmer ML, Reith W, Huwyler J, Irving M, King CG, Zippelius A, Hess C. Lötscher J, et al. Cell. 2022 Feb 17;185(4):585-602.e29. doi: 10.1016/j.cell.2021.12.039. Epub 2022 Jan 19. Cell. 2022. PMID: 35051368 Free article.
Mitochondria-Endoplasmic Reticulum Contact Sites Function as Immunometabolic Hubs that Orchestrate the Rapid Recall Response of Memory CD8+ T Cells.
Bantug GR, Fischer M, Grählert J, Balmer ML, Unterstab G, Develioglu L, Steiner R, Zhang L, Costa ASH, Gubser PM, Burgener AV, Sauder U, Löliger J, Belle R, Dimeloe S, Lötscher J, Jauch A, Recher M, Hönger G, Hall MN, Romero P, Frezza C, Hess C. Bantug GR, et al. Among authors: lotscher j. Immunity. 2018 Mar 20;48(3):542-555.e6. doi: 10.1016/j.immuni.2018.02.012. Epub 2018 Mar 6. Immunity. 2018. PMID: 29523440 Free PMC article.
SDHA gain-of-function engages inflammatory mitochondrial retrograde signaling via KEAP1-Nrf2.
Burgener AV, Bantug GR, Meyer BJ, Higgins R, Ghosh A, Bignucolo O, Ma EH, Loeliger J, Unterstab G, Geigges M, Steiner R, Enamorado M, Ivanek R, Hunziker D, Schmidt A, Müller-Durovic B, Grählert J, Epple R, Dimeloe S, Lötscher J, Sauder U, Ebnöther M, Burger B, Heijnen I, Martínez-Cano S, Cantoni N, Brücker R, Kahlert CR, Sancho D, Jones RG, Navarini A, Recher M, Hess C. Burgener AV, et al. Among authors: lotscher j. Nat Immunol. 2019 Oct;20(10):1311-1321. doi: 10.1038/s41590-019-0482-2. Epub 2019 Sep 16. Nat Immunol. 2019. PMID: 31527833
Diapedesis-Induced Integrin Signaling via LFA-1 Facilitates Tissue Immunity by Inducing Intrinsic Complement C3 Expression in Immune Cells.
Kolev M, West EE, Kunz N, Chauss D, Moseman EA, Rahman J, Freiwald T, Balmer ML, Lötscher J, Dimeloe S, Rosser EC, Wedderburn LR, Mayer-Barber KD, Bohrer A, Lavender P, Cope A, Wang L, Kaplan MJ, Moutsopoulos NM, McGavern D, Holland SM, Hess C, Kazemian M, Afzali B, Kemper C. Kolev M, et al. Among authors: lotscher j. Immunity. 2020 Mar 17;52(3):513-527.e8. doi: 10.1016/j.immuni.2020.02.006. Immunity. 2020. PMID: 32187519 Free PMC article.
Memory CD8+ T Cells Balance Pro- and Anti-inflammatory Activity by Reprogramming Cellular Acetate Handling at Sites of Infection.
Balmer ML, Ma EH, Thompson AJ, Epple R, Unterstab G, Lötscher J, Dehio P, Schürch CM, Warncke JD, Perrin G, Woischnig AK, Grählert J, Löliger J, Assmann N, Bantug GR, Schären OP, Khanna N, Egli A, Bubendorf L, Rentsch K, Hapfelmeier S, Jones RG, Hess C. Balmer ML, et al. Among authors: lotscher j. Cell Metab. 2020 Sep 1;32(3):457-467.e5. doi: 10.1016/j.cmet.2020.07.004. Epub 2020 Jul 31. Cell Metab. 2020. PMID: 32738204 Free article.
Deletion of SNX9 alleviates CD8 T cell exhaustion for effective cellular cancer immunotherapy.
Trefny MP, Kirchhammer N, Auf der Maur P, Natoli M, Schmid D, Germann M, Fernandez Rodriguez L, Herzig P, Lötscher J, Akrami M, Stinchcombe JC, Stanczak MA, Zingg A, Buchi M, Roux J, Marone R, Don L, Lardinois D, Wiese M, Jeker LT, Bentires-Alj M, Rossy J, Thommen DS, Griffiths GM, Läubli H, Hess C, Zippelius A. Trefny MP, et al. Among authors: lotscher j. Nat Commun. 2023 Feb 2;14(1):86. doi: 10.1038/s41467-022-35583-w. Nat Commun. 2023. PMID: 36732507 Free PMC article.
Real-Time Volatile Metabolomics Analysis of Dendritic Cells.
Arnold K, Dehio P, Lötscher J, Singh KD, García-Gómez D, Hess C, Sinues P, Balmer ML. Arnold K, et al. Among authors: lotscher j. Anal Chem. 2023 Jun 27;95(25):9415-9421. doi: 10.1021/acs.analchem.3c00516. Epub 2023 Jun 13. Anal Chem. 2023. PMID: 37311562 Free PMC article.
Immunologic and Genetic Contributors to CD46-Dependent Immune Dysregulation.
Meyer BJ, Kunz N, Seki S, Higgins R, Ghosh A, Hupfer R, Baldrich A, Hirsiger JR, Jauch AJ, Burgener AV, Lötscher J, Aschwanden M, Dickenmann M, Stegert M, Berger CT, Daikeler T, Heijnen I, Navarini AA, Rudin C, Yamamoto H, Kemper C, Hess C, Recher M. Meyer BJ, et al. Among authors: lotscher j. J Clin Immunol. 2023 Nov;43(8):1840-1856. doi: 10.1007/s10875-023-01547-y. Epub 2023 Jul 21. J Clin Immunol. 2023. PMID: 37477760 Free PMC article.
17 results