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Chronic edible dosing of Δ9-tetrahydrocannabinol (THC) in nonhuman primates reduces systemic platelet activity and function.
Reitsma SE, Lakshmanan HHS, Johnson J, Pang J, Parra-Izquierdo I, Melrose AR, Choi J, Anderson DEJ, Hinds MT, Stevens JF, Aslan JE, McCarty OJT, Lo JO. Reitsma SE, et al. Among authors: pang j. Am J Physiol Cell Physiol. 2022 Mar 1;322(3):C370-C381. doi: 10.1152/ajpcell.00373.2021. Epub 2022 Jan 26. Am J Physiol Cell Physiol. 2022. PMID: 35080922 Free PMC article.
p21 activated kinase signaling coordinates glycoprotein receptor VI-mediated platelet aggregation, lamellipodia formation, and aggregate stability under shear.
Aslan JE, Itakura A, Haley KM, Tormoen GW, Loren CP, Baker SM, Pang J, Chernoff J, McCarty OJ. Aslan JE, et al. Among authors: pang j. Arterioscler Thromb Vasc Biol. 2013 Jul;33(7):1544-51. doi: 10.1161/ATVBAHA.112.301165. Epub 2013 May 2. Arterioscler Thromb Vasc Biol. 2013. PMID: 23640496 Free PMC article.
The PAK system links Rho GTPase signaling to thrombin-mediated platelet activation.
Aslan JE, Baker SM, Loren CP, Haley KM, Itakura A, Pang J, Greenberg DL, David LL, Manser E, Chernoff J, McCarty OJ. Aslan JE, et al. Among authors: pang j. Am J Physiol Cell Physiol. 2013 Sep;305(5):C519-28. doi: 10.1152/ajpcell.00418.2012. Epub 2013 Jun 19. Am J Physiol Cell Physiol. 2013. PMID: 23784547 Free PMC article.
Lysine acetyltransfer supports platelet function.
Aslan JE, Rigg RA, Nowak MS, Loren CP, Baker-Groberg SM, Pang J, David LL, McCarty OJ. Aslan JE, et al. Among authors: pang j. J Thromb Haemost. 2015 Oct;13(10):1908-17. doi: 10.1111/jth.13070. Epub 2015 Aug 29. J Thromb Haemost. 2015. PMID: 26256950 Free PMC article.
4,068 results