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AKT-AMPKα-mTOR-dependent HIF-1α Activation is a New Therapeutic Target for Cancer Treatment: A Novel Approach to Repositioning the Antidiabetic Drug Sitagliptin for the Management of Hepatocellular Carcinoma.
Abd El-Fattah EE, Saber S, Youssef ME, Eissa H, El-Ahwany E, Amin NA, Alqarni M, Batiha GE, Obaidullah AJ, Kaddah MMY, Ahmed Gaafar AG, Mourad AAE, Mostafa-Hedeab G, Abdelhamid AM. Abd El-Fattah EE, et al. Among authors: ahmed gaafar ag. Front Pharmacol. 2022 Jan 12;12:720173. doi: 10.3389/fphar.2021.720173. eCollection 2021. Front Pharmacol. 2022. PMID: 35095479 Free PMC article.
Interference With the AMPKα/mTOR/NLRP3 Signaling and the IL-23/IL-17 Axis Effectively Protects Against the Dextran Sulfate Sodium Intoxication in Rats: A New Paradigm in Empagliflozin and Metformin Reprofiling for the Management of Ulcerative Colitis.
Youssef ME, Abd El-Fattah EE, Abdelhamid AM, Eissa H, El-Ahwany E, Amin NA, Hetta HF, Mahmoud MH, Batiha GE, Gobba N, Ahmed Gaafar AG, Saber S. Youssef ME, et al. Among authors: ahmed gaafar ag. Front Pharmacol. 2021 Aug 16;12:719984. doi: 10.3389/fphar.2021.719984. eCollection 2021. Front Pharmacol. 2021. PMID: 34489707 Free PMC article.
Design and Synthesis of Newly Synthesized Acrylamide Derivatives as Potential Chemotherapeutic Agents against MCF-7 Breast Cancer Cell Line Lodged on PEGylated Bilosomal Nano-Vesicles for Improving Cytotoxic Activity.
Zaki I, Abou-Elkhair RAI, Abu Almaaty AH, A Abu Ali O, Fayad E, Ahmed Gaafar AG, Zakaria MY. Zaki I, et al. Among authors: ahmed gaafar ag. Pharmaceuticals (Basel). 2021 Oct 4;14(10):1021. doi: 10.3390/ph14101021. Pharmaceuticals (Basel). 2021. PMID: 34681245 Free PMC article.