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Page 1
AKT-AMPKα-mTOR-dependent HIF-1α Activation is a New Therapeutic Target for Cancer Treatment: A Novel Approach to Repositioning the Antidiabetic Drug Sitagliptin for the Management of Hepatocellular Carcinoma.
Abd El-Fattah EE, Saber S, Youssef ME, Eissa H, El-Ahwany E, Amin NA, Alqarni M, Batiha GE, Obaidullah AJ, Kaddah MMY, Ahmed Gaafar AG, Mourad AAE, Mostafa-Hedeab G, Abdelhamid AM. Abd El-Fattah EE, et al. Among authors: amin na. Front Pharmacol. 2022 Jan 12;12:720173. doi: 10.3389/fphar.2021.720173. eCollection 2021. Front Pharmacol. 2022. PMID: 35095479 Free PMC article.
A Novel Combination Therapy Using Rosuvastatin and Lactobacillus Combats Dextran Sodium Sulfate-Induced Colitis in High-Fat Diet-Fed Rats by Targeting the TXNIP/NLRP3 Interaction and Influencing Gut Microbiome Composition.
Saber S, Abd El-Fattah EE, Yahya G, Gobba NA, Maghmomeh AO, Khodir AE, Mourad AAE, Saad AS, Mohammed HG, Nouh NA, Shata A, Amin NA, Abou El-Rous M, Girgis S, El-Ahwany E, Khalaf EM, El-Kott AF, El-Baz AM. Saber S, et al. Among authors: amin na. Pharmaceuticals (Basel). 2021 Apr 8;14(4):341. doi: 10.3390/ph14040341. Pharmaceuticals (Basel). 2021. PMID: 33917884 Free PMC article.
The Supportive Role of NSC328382, a P2X7R Antagonist, in Enhancing the Inhibitory Effect of CRID3 on NLRP3 Inflammasome Activation in Rats with Dextran Sodium Sulfate-Induced Colitis.
Saber S, Yahya G, Gobba NA, Sharaf H, Alshaman R, Alattar A, Amin NA, El-Shedody R, Aboutouk FH, Abd El-Galeel Y, El-Hefnawy A, Shabaka D, Khalifa A, Saleh R, Osama D, El-Zoghby G, Youssef ME. Saber S, et al. Among authors: amin na. J Inflamm Res. 2021 Jul 21;14:3443-3463. doi: 10.2147/JIR.S315938. eCollection 2021. J Inflamm Res. 2021. PMID: 34321905 Free PMC article.
Albendazole-loaded cubosomes interrupt the ERK1/2-HIF-1α-p300/CREB axis in mice intoxicated with diethylnitrosamine: A new paradigm in drug repurposing for the inhibition of hepatocellular carcinoma progression.
Saber S, Nasr M, Saad AS, Mourad AAE, Gobba NA, Shata A, Hafez AM, Elsergany RN, Elagamy HI, El-Ahwany E, Amin NA, Girgis S, Elewa YHA, Mahmoud MH, Batiha GE, El-Rous MA, Kamal I, Kaddah MMY, Khodir AE. Saber S, et al. Among authors: amin na. Biomed Pharmacother. 2021 Oct;142:112029. doi: 10.1016/j.biopha.2021.112029. Epub 2021 Aug 17. Biomed Pharmacother. 2021. PMID: 34416629 Free article.
Interference With the AMPKα/mTOR/NLRP3 Signaling and the IL-23/IL-17 Axis Effectively Protects Against the Dextran Sulfate Sodium Intoxication in Rats: A New Paradigm in Empagliflozin and Metformin Reprofiling for the Management of Ulcerative Colitis.
Youssef ME, Abd El-Fattah EE, Abdelhamid AM, Eissa H, El-Ahwany E, Amin NA, Hetta HF, Mahmoud MH, Batiha GE, Gobba N, Ahmed Gaafar AG, Saber S. Youssef ME, et al. Among authors: amin na. Front Pharmacol. 2021 Aug 16;12:719984. doi: 10.3389/fphar.2021.719984. eCollection 2021. Front Pharmacol. 2021. PMID: 34489707 Free PMC article.
Blunting p38 MAPKα and ERK1/2 activities by empagliflozin enhances the antifibrotic effect of metformin and augments its AMPK-induced NF-κB inactivation in mice intoxicated with carbon tetrachloride.
Abdelhamid AM, Youssef ME, Abd El-Fattah EE, Gobba NA, Gaafar AGA, Girgis S, Shata A, Hafez AM, El-Ahwany E, Amin NA, Shahien MA, Abd-Eldayem MA, Abou-Elrous M, Saber S. Abdelhamid AM, et al. Among authors: amin na. Life Sci. 2021 Dec 1;286:120070. doi: 10.1016/j.lfs.2021.120070. Epub 2021 Oct 21. Life Sci. 2021. PMID: 34688695
Empagliflozin adjunct with metformin for the inhibition of hepatocellular carcinoma progression: Emerging approach for new application.
Abdelhamid AM, Saber S, Youssef ME, Gaafar AGA, Eissa H, Abd-Eldayem MA, Alqarni M, Batiha GE, Obaidullah AJ, Shahien MA, El-Ahwany E, Amin NA, Etman MA, Kaddah MMY, Abd El-Fattah EE. Abdelhamid AM, et al. Among authors: amin na. Biomed Pharmacother. 2022 Jan;145:112455. doi: 10.1016/j.biopha.2021.112455. Epub 2021 Nov 26. Biomed Pharmacother. 2022. PMID: 34844106 Free article.
The dynamic interplay between AMPK/NFκB signaling and NLRP3 is a new therapeutic target in inflammation: Emerging role of dapagliflozin in overcoming lipopolysaccharide-mediated lung injury.
Abd El-Fattah EE, Saber S, Mourad AAE, El-Ahwany E, Amin NA, Cavalu S, Yahya G, Saad AS, Alsharidah M, Shata A, Sami HM, Kaddah MMY, Ghanim AMH. Abd El-Fattah EE, et al. Among authors: amin na. Biomed Pharmacother. 2022 Mar;147:112628. doi: 10.1016/j.biopha.2022.112628. Epub 2022 Jan 12. Biomed Pharmacother. 2022. PMID: 35032769 Free article.
55 results