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AKT-AMPKα-mTOR-dependent HIF-1α Activation is a New Therapeutic Target for Cancer Treatment: A Novel Approach to Repositioning the Antidiabetic Drug Sitagliptin for the Management of Hepatocellular Carcinoma.
Abd El-Fattah EE, Saber S, Youssef ME, Eissa H, El-Ahwany E, Amin NA, Alqarni M, Batiha GE, Obaidullah AJ, Kaddah MMY, Ahmed Gaafar AG, Mourad AAE, Mostafa-Hedeab G, Abdelhamid AM. Abd El-Fattah EE, et al. Among authors: eissa h. Front Pharmacol. 2022 Jan 12;12:720173. doi: 10.3389/fphar.2021.720173. eCollection 2021. Front Pharmacol. 2022. PMID: 35095479 Free PMC article.
Interference With the AMPKα/mTOR/NLRP3 Signaling and the IL-23/IL-17 Axis Effectively Protects Against the Dextran Sulfate Sodium Intoxication in Rats: A New Paradigm in Empagliflozin and Metformin Reprofiling for the Management of Ulcerative Colitis.
Youssef ME, Abd El-Fattah EE, Abdelhamid AM, Eissa H, El-Ahwany E, Amin NA, Hetta HF, Mahmoud MH, Batiha GE, Gobba N, Ahmed Gaafar AG, Saber S. Youssef ME, et al. Among authors: eissa h. Front Pharmacol. 2021 Aug 16;12:719984. doi: 10.3389/fphar.2021.719984. eCollection 2021. Front Pharmacol. 2021. PMID: 34489707 Free PMC article.
Empagliflozin adjunct with metformin for the inhibition of hepatocellular carcinoma progression: Emerging approach for new application.
Abdelhamid AM, Saber S, Youssef ME, Gaafar AGA, Eissa H, Abd-Eldayem MA, Alqarni M, Batiha GE, Obaidullah AJ, Shahien MA, El-Ahwany E, Amin NA, Etman MA, Kaddah MMY, Abd El-Fattah EE. Abdelhamid AM, et al. Among authors: eissa h. Biomed Pharmacother. 2022 Jan;145:112455. doi: 10.1016/j.biopha.2021.112455. Epub 2021 Nov 26. Biomed Pharmacother. 2022. PMID: 34844106 Free article.
Combining the HSP90 inhibitor TAS-116 with metformin effectively degrades the NLRP3 and attenuates inflammasome activation in rats: A new management paradigm for ulcerative colitis.
Shaaban AA, Abdelhamid AM, Shaker ME, Cavalu S, Maghiar AM, Alsayegh AA, Babalghith AO, El-Ahwany E, Amin NA, Mohammed OA, Eissa H, Gaafar AGA, Batiha GE, Saber S. Shaaban AA, et al. Among authors: eissa h. Biomed Pharmacother. 2022 Sep;153:113247. doi: 10.1016/j.biopha.2022.113247. Epub 2022 Jun 17. Biomed Pharmacother. 2022. PMID: 35724510 Free article.
A novel therapeutic combination of dapagliflozin, Lactobacillus and crocin attenuates diabetic cardiomyopathy in rats: Role of oxidative stress, gut microbiota, and PPARγ activation.
Khalaf EM, Hassan HM, El-Baz AM, Shata A, Khodir AE, Yousef ME, Elgharabawy RM, Nouh NA, Saleh S, Bin-Meferij MM, El-Kott AF, El-Sokkary MMA, Eissa H. Khalaf EM, et al. Among authors: eissa h. Eur J Pharmacol. 2022 Sep 15;931:175172. doi: 10.1016/j.ejphar.2022.175172. Epub 2022 Aug 6. Eur J Pharmacol. 2022. PMID: 35944619
Naturally occurring benzophenones and xanthones from Garcinia smeathmannii (Planch. & Triana) Oliv. displayed anti-inflammatory effects by modulating the activities of inflammatory mediators in LPS-stimulated RAW 264.7 macrophages.
Jeelani M, Fouotsa H, Mohammed OA, Alfaifi J, Adebayo S, Ahmed MM, Yahia AIO, Eissa H, Bahashwan E, Mohammed NA, Alotaibi YA, Asiri AY, Rezigallah A, Alharthi MH, Dzoyem JP, Isa AI. Jeelani M, et al. Among authors: eissa h. Front Pharmacol. 2024 Jun 3;15:1370073. doi: 10.3389/fphar.2024.1370073. eCollection 2024. Front Pharmacol. 2024. PMID: 38887547 Free PMC article.
97 results