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Page 1
AKT-AMPKα-mTOR-dependent HIF-1α Activation is a New Therapeutic Target for Cancer Treatment: A Novel Approach to Repositioning the Antidiabetic Drug Sitagliptin for the Management of Hepatocellular Carcinoma.
Abd El-Fattah EE, Saber S, Youssef ME, Eissa H, El-Ahwany E, Amin NA, Alqarni M, Batiha GE, Obaidullah AJ, Kaddah MMY, Ahmed Gaafar AG, Mourad AAE, Mostafa-Hedeab G, Abdelhamid AM. Abd El-Fattah EE, et al. Among authors: youssef me. Front Pharmacol. 2022 Jan 12;12:720173. doi: 10.3389/fphar.2021.720173. eCollection 2021. Front Pharmacol. 2022. PMID: 35095479 Free PMC article.
BBG enhances OLT1177-induced NLRP3 inflammasome inactivation by targeting P2X7R/NLRP3 and MyD88/NF-κB signaling in DSS-induced colitis in rats.
Saber S, Youssef ME, Sharaf H, Amin NA, El-Shedody R, Aboutouk FH, El-Galeel YA, El-Hefnawy A, Shabaka D, Khalifa A, Saleh RA, Osama D, El-Zoghby G, Gobba NA. Saber S, et al. Among authors: youssef me. Life Sci. 2021 Apr 1;270:119123. doi: 10.1016/j.lfs.2021.119123. Epub 2021 Feb 3. Life Sci. 2021. PMID: 33548287
The Supportive Role of NSC328382, a P2X7R Antagonist, in Enhancing the Inhibitory Effect of CRID3 on NLRP3 Inflammasome Activation in Rats with Dextran Sodium Sulfate-Induced Colitis.
Saber S, Yahya G, Gobba NA, Sharaf H, Alshaman R, Alattar A, Amin NA, El-Shedody R, Aboutouk FH, Abd El-Galeel Y, El-Hefnawy A, Shabaka D, Khalifa A, Saleh R, Osama D, El-Zoghby G, Youssef ME. Saber S, et al. Among authors: youssef me. J Inflamm Res. 2021 Jul 21;14:3443-3463. doi: 10.2147/JIR.S315938. eCollection 2021. J Inflamm Res. 2021. PMID: 34321905 Free PMC article.
Interference With the AMPKα/mTOR/NLRP3 Signaling and the IL-23/IL-17 Axis Effectively Protects Against the Dextran Sulfate Sodium Intoxication in Rats: A New Paradigm in Empagliflozin and Metformin Reprofiling for the Management of Ulcerative Colitis.
Youssef ME, Abd El-Fattah EE, Abdelhamid AM, Eissa H, El-Ahwany E, Amin NA, Hetta HF, Mahmoud MH, Batiha GE, Gobba N, Ahmed Gaafar AG, Saber S. Youssef ME, et al. Front Pharmacol. 2021 Aug 16;12:719984. doi: 10.3389/fphar.2021.719984. eCollection 2021. Front Pharmacol. 2021. PMID: 34489707 Free PMC article.
Blunting p38 MAPKα and ERK1/2 activities by empagliflozin enhances the antifibrotic effect of metformin and augments its AMPK-induced NF-κB inactivation in mice intoxicated with carbon tetrachloride.
Abdelhamid AM, Youssef ME, Abd El-Fattah EE, Gobba NA, Gaafar AGA, Girgis S, Shata A, Hafez AM, El-Ahwany E, Amin NA, Shahien MA, Abd-Eldayem MA, Abou-Elrous M, Saber S. Abdelhamid AM, et al. Among authors: youssef me. Life Sci. 2021 Dec 1;286:120070. doi: 10.1016/j.lfs.2021.120070. Epub 2021 Oct 21. Life Sci. 2021. PMID: 34688695
Empagliflozin adjunct with metformin for the inhibition of hepatocellular carcinoma progression: Emerging approach for new application.
Abdelhamid AM, Saber S, Youssef ME, Gaafar AGA, Eissa H, Abd-Eldayem MA, Alqarni M, Batiha GE, Obaidullah AJ, Shahien MA, El-Ahwany E, Amin NA, Etman MA, Kaddah MMY, Abd El-Fattah EE. Abdelhamid AM, et al. Among authors: youssef me. Biomed Pharmacother. 2022 Jan;145:112455. doi: 10.1016/j.biopha.2021.112455. Epub 2021 Nov 26. Biomed Pharmacother. 2022. PMID: 34844106 Free article.
Coomassie brilliant blue G-250 dye attenuates bleomycin-induced lung fibrosis by regulating the NF-κB and NLRP3 crosstalk: A novel approach for filling an unmet medical need.
Zohny MH, Cavalu S, Youssef ME, Kaddah MMY, Mourad AAE, Gaafar AGA, El-Ahwany E, Amin NA, Arakeep HM, Shata A, Saleh S, Hafez MM, Elazab ST, Abdelhady R, El Shahat RM, Yahya G, Saber S. Zohny MH, et al. Among authors: youssef me. Biomed Pharmacother. 2022 Apr;148:112723. doi: 10.1016/j.biopha.2022.112723. Epub 2022 Feb 21. Biomed Pharmacother. 2022. PMID: 35202914 Free article.
Carbocisteine as a Modulator of Nrf2/HO-1 and NFκB Interplay in Rats: New Inspiration for the Revival of an Old Drug for Treating Ulcerative Colitis.
Abdelhamid AM, Youssef ME, Cavalu S, Mostafa-Hedeab G, Youssef A, Elazab ST, Ibrahim S, Allam S, Elgharabawy RM, El-Ahwany E, Amin NA, Shata A, Mohammed OA, Ibrahim Abdeldaiem MS, Alhowail A, El-Saber Batiha G, El-Mahmoudy EA, Attia M, Allam A, Zaater MY, Osman MM, Nader M, Taha A, Makarem NA, Saber S. Abdelhamid AM, et al. Among authors: youssef a, youssef me. Front Pharmacol. 2022 Jun 8;13:887233. doi: 10.3389/fphar.2022.887233. eCollection 2022. Front Pharmacol. 2022. PMID: 35754464 Free PMC article.
Ambroxol, a mucolytic agent, boosts HO-1, suppresses NF-κB, and decreases the susceptibility of the inflamed rat colon to apoptosis: A new treatment option for treating ulcerative colitis.
Cavalu S, Sharaf H, Saber S, Youssef ME, Abdelhamid AM, Mourad AAE, Ibrahim S, Allam S, Elgharabawy RM, El-Ahwany E, Amin NA, Shata A, Eldegla M, Atef M, Aboraya M, Mohamed M, Anz N, Elmotelb DA, Gabr F, Elzablawy D, Hamada M, Yehia A, Osama D, Mohammed OA. Cavalu S, et al. Among authors: youssef me. FASEB J. 2022 Sep;36(9):e22496. doi: 10.1096/fj.202200749R. FASEB J. 2022. PMID: 35947115
55 results