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Spatial transcriptomic analysis reveals inflammatory foci defined by senescent cells in the white matter, hippocampi and cortical grey matter in the aged mouse brain.
Kiss T, Nyúl-Tóth Á, DelFavero J, Balasubramanian P, Tarantini S, Faakye J, Gulej R, Ahire C, Ungvari A, Yabluchanskiy A, Wiley G, Garman L, Ungvari Z, Csiszar A. Kiss T, et al. Among authors: wiley g. Geroscience. 2022 Apr;44(2):661-681. doi: 10.1007/s11357-022-00521-7. Epub 2022 Jan 31. Geroscience. 2022. PMID: 35098444 Free PMC article.
Optimized monoclonal antibody treatment against ELTD1 for GBM in a G55 xenograft mouse model.
Zalles M, Smith N, Ziegler J, Saunders D, Remerowski S, Thomas L, Gulej R, Mamedova N, Lerner M, Fung KM, Chung J, Hwang K, Jin J, Wiley G, Brown C, Battiste J, Wren JD, Towner RA. Zalles M, et al. Among authors: wiley g. J Cell Mol Med. 2020 Jan;24(2):1738-1749. doi: 10.1111/jcmm.14867. Epub 2019 Dec 21. J Cell Mol Med. 2020. PMID: 31863639 Free PMC article.
Mutated KLF4(K409Q) in meningioma binds STRs and activates FGF3 gene expression.
Tsytsykova AV, Wiley G, Li C, Pelikan RC, Garman L, Acquah FA, Mooers BHM, Tsitsikov EN, Dunn IF. Tsytsykova AV, et al. Among authors: wiley g. iScience. 2022 Aug 3;25(8):104839. doi: 10.1016/j.isci.2022.104839. eCollection 2022 Aug 19. iScience. 2022. PMID: 35996584 Free PMC article.
Single-cell analysis of glandular T cell receptors in Sjögren's syndrome.
Joachims ML, Leehan KM, Lawrence C, Pelikan RC, Moore JS, Pan Z, Rasmussen A, Radfar L, Lewis DM, Grundahl KM, Kelly JA, Wiley GB, Shugay M, Chudakov DM, Lessard CJ, Stone DU, Scofield RH, Montgomery CG, Sivils KL, Thompson LF, Farris AD. Joachims ML, et al. Among authors: wiley gb. JCI Insight. 2016 Jun 2;1(8):e85609. doi: 10.1172/jci.insight.85609. JCI Insight. 2016. PMID: 27358913 Free PMC article.
OKN-007 Increases temozolomide (TMZ) Sensitivity and Suppresses TMZ-Resistant Glioblastoma (GBM) Tumor Growth.
Towner RA, Smith N, Saunders D, Brown CA, Cai X, Ziegler J, Mallory S, Dozmorov MG, Coutinho De Souza P, Wiley G, Kim K, Kang S, Kong DS, Kim YT, Fung KM, Wren JD, Battiste J. Towner RA, et al. Among authors: wiley g. Transl Oncol. 2019 Feb;12(2):320-335. doi: 10.1016/j.tranon.2018.10.002. Epub 2018 Nov 20. Transl Oncol. 2019. PMID: 30468988 Free PMC article.
Role of Systemic Lupus Erythematosus Risk Variants With Opposing Functional Effects as a Driver of Hypomorphic Expression of TNIP1 and Other Genes Within a Three-Dimensional Chromatin Network.
Pasula S, Tessneer KL, Fu Y, Gopalakrishnan J, Pelikan RC, Kelly JA, Wiley GB, Wiley MM, Gaffney PM. Pasula S, et al. Arthritis Rheumatol. 2020 May;72(5):780-790. doi: 10.1002/art.41188. Epub 2020 Mar 30. Arthritis Rheumatol. 2020. PMID: 31804013 Free PMC article.
Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus.
Adrianto I, Wen F, Templeton A, Wiley G, King JB, Lessard CJ, Bates JS, Hu Y, Kelly JA, Kaufman KM, Guthridge JM, Alarcón-Riquelme ME; BIOLUPUS and GENLES Networks; Anaya JM, Bae SC, Bang SY, Boackle SA, Brown EE, Petri MA, Gallant C, Ramsey-Goldman R, Reveille JD, Vila LM, Criswell LA, Edberg JC, Freedman BI, Gregersen PK, Gilkeson GS, Jacob CO, James JA, Kamen DL, Kimberly RP, Martin J, Merrill JT, Niewold TB, Park SY, Pons-Estel BA, Scofield RH, Stevens AM, Tsao BP, Vyse TJ, Langefeld CD, Harley JB, Moser KL, Webb CF, Humphrey MB, Montgomery CG, Gaffney PM. Adrianto I, et al. Among authors: wiley g. Nat Genet. 2011 Mar;43(3):253-8. doi: 10.1038/ng.766. Epub 2011 Feb 20. Nat Genet. 2011. PMID: 21336280 Free PMC article.
84 results